Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"sensorimotor cortex"”.
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Effects of Neuronal Nogo-A on Properties of Excitatory Synapses of the Sensorimotor Cortex
… of Nogo-A at the excitatory synapse of the neocortex, we used RNAi directed against Nogo-A and delivered it to the developing rat sensorimotor cortex via AAV2/8, a neurotropic vector. This resulted in lowered density of dendritic spines, which are known to house over 90% of excitatory …
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Contribution of microglial reactivity to olfactory ensheathing cell migration in vivo
… of T11 following aspiration of the contralateral sensorimotor cortex. This timing data from this study demonstrated a prominent microglial activation in the right dCST of T11 eight weeks after sensorimotor cortex injury indicating the microglial response to WD of dCST axons was very slow to …
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Lesion-induced Synaptic Remodelling In The Rat Red Nucleus
… from the deep cerebellar nuclei and the sensorimotor cortex were studied using anterograde and retrograde transport of horseradish peroxidase conjugated to wheat germ agglutinin (HRP-WGA), as well as retrograde transport of the fluorochromes Fast Blue and Nuclear Yellow. To examine the …
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The Role of Nogo-A in Memory and Neuronal Plasticity in the Aged Rodent Brain
… improves recovery of skilled forelimb sensorimotor function in adult and aged rats after an ischemic stroke lesion to the sensorimotor cortex. Furthermore, this recovery was correlated with axonal sprouting from intact pathways to denervated areas, as well as dendritic sprouting and …
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From prosodic structure to acoustic saliency: an fMRI investigation of speech rate, clarity, and emphasis
… by increased activity in right middle premotor cortex and supplementary motor area, and bilateral primary sensorimotor cortex. These findings are consistent with right-lateralized motor planning of prosodic variation in emphatic speech. Clear speech involved an increase in average vowel and …
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Investigation of the Clinical Utility of the Spatio-Spectral Dynamics of Sensorimotor ECoG in Response to Different Somatosensory Stimulation Modalities in Human Subjects
… We hypothesized that automated mapping of the sensorimotor cortex could be achieved with high-density electrocorticogram (ECoG) grids. The recorded neural data interpretation can be achieved with machine learning algorithms. Additionally, we used the unique opportunity to assess sensorimotor …
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Plasticity of the cortical representation of finger extensors induced by paired associative stimulation
… induces significant neuroplastic changes in the sensorimotor cortex. Explicitly, VR based PAS facilitates corticospinal excitability in the ipsilesional sensorimotor cortex. As a result, this dissertation provides a new methodological and technical framework to condition the standard PAS paradigm …
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Motor imagery classification using sparse representation of EEG signals
… the electrodes are reduced to those near the sensorimotor cortex which are believed to be crucial for motor preparation and imagination. In a second approach, we try to incorporate the effect of spatial correlation across the neighboring electrodes near the sensorimotor cortex. To this end, …
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Virtual reality visual feedback and its effect on brain excitability
… excitability of distinct neural networks in the sensorimotor cortex. The objective is to explore neural responses to visual feedback of motor activities performed in complex virtual environments during functional magnetic resonance imaging (fMRI), and to identify sensory manipulations that could …
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Auto detection in autism
… are also performed. A significant overlap in the sensorimotor cortex is found between the various methods suggesting that the automatic detecting method presented does provide accurate detection and localization.
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Towards a Better Understanding of Facial Movements: Computational Models for Perception, Characterization, and Neural Production
… a unique dataset of single-cell recordings from sensorimotor cortex regions and behavioral video recordings of spontaneous, unconstrained, and naturalistic facial movements of macaques.This research first focused on developing computational models capable of separating facial movements from other …
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Beta oscillations in frontal cortex and striatum represent post-processing of successful behavior
Beta band (13-30 Hz) oscillations in sensorimotor cortex are associated with motor performance, but the nature of this relationship is not clear. Recently, excessive beta activity in cortico-basal ganglia circuits has been recognized as a hallmark of Parkinson's disease. Renewed interest in beta …
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Personalized Multimodal MRI-Guided Theta Burst Brain Stimulation for Effective Memory Enhancement in Mild Cognitive Impairment
… of baseline functional connectivity within the sensorimotor cortex. This approach highlights the inter-individual variability in TMS effects and the potential for tailored therapeutic strategies based on individual neurophysiological profiles. The dissertation concludes with a synthesis of …
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A COMBINATION THERAPY OF NICOTINAMIDE AND PROGESTERONE FOR FUNCTIONAL RECOVERY FOLLOWING TRAUMATIC BRAIN INJURY
… received a cortical contusion injury over the sensorimotor cortex and were treated with either nicotinamide (75 mg/kg, i.p. NAM loading dose, 12 mg/kg/hr NAM, s.c. over 72 hrs), Prog (10 mg/kg Prog, i.p. over 72 hrs), NAM and Prog(75 mg/kg, i.p. NAM loading dose, followed by continuous infusion …
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fMRI for mapping the plastic somatotopy of primary somatosensory cortex - Development and clinical applications
… for fMRI mapping of the primary somatosensory cortex (S1) are optimised and subsequently applied in studies where a plastic reorganisation of S1 is hypothesised. Initially, the impact of spatial resolution and smoothing on fMRI data of detailed S1 activation was investigated using a theoretical …
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Revealing mnemonic representations of the body in the brain
… method to isolate brain activity arising in sensorimotor cortex from concomitant visual activity that is elicited at the sight of visually perceived body stimuli. Chapter 2.5 outlines how the stimuli for the experiments of this thesis were created. Chapter 3 reports the first study looking …
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Identifying the Neural Correlates of Swallowing in Two Age Groups Using fMRI
… activations mainly in the primary somatosensory cortex of young adults during most tasks examined (p<0.05). Within and between group comparisons of hemispheric preference failed to find groupwise significant lateralization of the entire sensorimotor cortex or a significant group difference in …
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Electrophysiological Recording of the Brain, Visualization, Prediction, and Interconnectivity
… investigating the inter-coupling between the sensorimotor cortex and basal ganglia and how cortico-basal ganglia coupling changes with respect to the movement. The association of coherence with power suggests that a coupling in neural activity between the basal ganglia and the cortical region …
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Binge Alcohol and Recovery After Traumatic Brain Injury
… adult, male, Sprague Dawley rats on a skilled sensorimotor test, the forelimb reaching task. Following successful learning, animals were administered either a repeated binge regimen of ethanol (2g/kg) for three consecutive days or a single binge dose. One hour after the final ethanol dose, rats …
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Independent Component Analysis of Event-Related Electroencephalography During Speech and Non-Speech Discrimination: : Implications for the Sensorimotor ∆∞ Rhythm in Speech Processing
… The functional significance of sensorimotor integration in acoustic speech processing is unclear despite more than three decades of neuroimaging research. Constructivist theories have long speculated that listeners make predictions about articulatory goals functioning to weight …
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