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Showing 1 to 20 of 50 for “"selenite"”.
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Lens calcium homeostasis and selenite cataract
… Ca2+ accompanies cataract formation induced by selenite. The mechanism of selenite cataractogenesis involves calcium activation of calpain with subsequent proteolysis within the lens nucleus. This study was undertaken to investigate the biochemical mechanisms that lead to calcium accumulation in …
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Selenite influence on calcium metabolism of the rat lens
… has been associated with formation of cataracts. Selenite is known to influence the histological characteristics of the lens and also alter important biochemical functions. In the selenite induced cataract calcium levels increase as much as 5-fold above normal, the increase preceding appearance of …
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The action of selenite on ATP synthesis in rat lens
A subcutaneous injection of sodium selenite (30 umol/kg body weight) in 10â day old rats produced a cataract within 72 hours. Lens opacification was preceded by a 15% decrease in ATP content. Lens ATP did not fully recover to control concentrations by 11 days post-injection. A moderate correlation …
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Identification and Characterization of Factors Involved in Sodium Selenite Toxicity
… disorders. The inorganic form of Se, selenite (SeL) leads to reactive oxygen species (ROS) formation. Under physiological conditions, ROS modulate gene expression, active signaling cascades or even apoptosis. However, excessive ROS levels leads to oxidative stress, DNA damage and …
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Effects of selenite on metabolic events during the proliferation of canine mammary tumor cells
… correlated with cell growth inhibition caused by selenite supplementation. Greater quantities of cytosolic selenium-containing proteins and a nuclear selenium-containing protein were detected as the quantity of selenium within CMT-13 cells increased. One of the antiproliferation effects of …
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Antioxidant Intervention With manganese(Iii)-Salophen in the Selenite Cataract Model: Implications for Cataract Disease
… Mn(III)-salophen, as a therapeutic agent in the selenite cataract model. Mn(III)-salophen has been shown to protect E. coli colonies against oxidative stress but was untested in a eukaryotic system. A total dose of 300 mmol/kg, given IP in four equal 75 mmol/kg doses spaced four hours apart, …
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Involvement of cellular sulfhydryls in the selenite-mediated growth inhibition of canine mammary tumor cells in culture
… to examine the mechanism by which selenium as selenite inhibits the growth of some tumor cells. The ability of supplemental selenite to inhibit the in vitro growth of CMT-13 cells increased with culture density, concentration of selenite and length of exposure to selenite.
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Dosage Window of Selenium on Human Natural Killer Cytotoxicity and Neutrophilmediated Chemiluminescence
… the effects of in vitro incubation with sodium selenite on natural killer (NK)-mediated cytotoxicity and phagocyte chemiluminescence (CL) were examined. NK-mediated cytotoxicity and phagocyte CL were observed to be affected by added selenite. These changes generally included augmentation and …
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Selenium-induced Enhancement of Hematoporphyrin Derivative Phototoxicity in Murine Bladder Tumor Cells
… was observed that selenium in the form of sodium selenite enhanced Hpd-sensitized photodamage in MBT-2 cells under conditions where the selenite alone was non-toxic. Sodium selenite was found to enhance the fluorescence emission of Hpd and augment the Hpd-sensitized photooxidation of tryptophan. …
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Physiological, hormonal and metabolic alterations caused by selenium in rice seedlings
… seedlings was investigated. The application of selenite did not affect the of growth shoot of seedlings, but promoted the elongation of the primary root with reduction in the number and length of the lateral roots. There was a decrease in the concentrations of ethylene, 1- …
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Effects of sulfur complexation on intestinal transport and toxicity of metalloids in cell cultures
… higher cytotoxicity of selenosulfate compared to selenite for cancer cell lines led to the claim of replacing selenite by selenosulfate in anti-cancer therapies. In the first two studies of the present thesis, intestinal transport (e.g. bioavailability), cellular retention, and cytotoxicity of …
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Acute Selenium Toxicosis in Sheep
… pathological changes produced by sodium selenite in sheep following parenteral administration were evaluated.
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Study of Chemical States, Composition and Adsorption Behavior of Iron Coated Granular Activated Carbon (Fe-GAC) for Selenate Removal and Feasible Adsorbent Modifications
… ionic strength, which was not observed in selenite adsorption with the same adsorbent. Competitive adsorption with other four oxy-anions (SiO 32-, SO42-, PO4 3- and CO32-) showed that selenate removal efficiency was reduced to various degrees in the presence of each individual anion. …
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Acute and chronic effects of selenium on Daphnia pulex
… freshwater species. All data are expressed as selenite-selenium. Daphnia pulex had a 48 hr LC50 of 3.87 mg/l selenium. The 96 hr LC50 and EC50O values for Gambusia affinis and Physa sp. respectively, were 12.56 and 27.08 mg/l selenium. The sublethal effects of 0.2, 0.4, 0.6 and 0.8 mg/1 …
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Interactive effects of selenium on arsenic and cadmium induced toxicity in rainbow trout (Oncorhynchus mykiss)
… using trout hepatocytes in primary culture. Selenite and selenomethionine were used as the inorganic and organic chemical forms of selenium to understand the chemical species-dependent effects. Interactions at the organismal level were studied by feeding the fish with Artemia based diets …
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Selenium Distribution and Cycling in the Eastern Equatorial Pacific Ocean
… minimum zone off Peru. Dissolved selenate, selenite, and organic selenide, as well as particulate elemental selenium, were determined in water column samples. Nitrate and nitrite data were used to determine where denitrification was occurring and thus approximately where dissimilatory …
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Effects of selenium and vitamin B-6 on growth of chemically- induced transplanted tumors in BALB/c inbred mice
… after tumor cell inoculation, a series of sodium selenite injections (0.5 μg/.10 mL) were given to half of each treatment group and all controls. Mice were sacrificed two wk after tumor inoculation. Tumors were excised and weighed. Selenium-treated mice had significantly smaller tumors as compared …
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Nachweis von Salmonella spp. bei Landschildkröten
… resulted from RAPPAPORT-VASSILIADIS and selenite cystine enrichment broth at an incubation temperature of 35-37 °C. The higher critical temperature for incubation of RAPPAPORT-VASSILIADIS enrichment medium is 42 °C; especially Salmonella subspecies IIIb often are inhibited in this medium …
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Exploring combined effects of arsenic and selenium exposure on larval zebrafish (Danio rerio)
… (as arsenite), As 120 μg/L + Se 25 μg/L (as selenite), As 120 μg/L + Se 120 μg/L (as selenite), and As 120 μg/L + Se 2.5 μg/L (as selenomethionine, SeMet) until 4 days post-fertilization. There was no significant difference in the survival, hatching and deformity rate when fish were exposed …
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Dietary Effects of Selenium During Reproduction in the Rat (Lactation, Milk, Pregnancy, Bioavailability, Glutathione Peroxidase)
… (2) bioavailability of organic Se relative to selenite in the maternal diet during lactation, and (3) utilization of dietary Se during lactation.
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