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Showing 1 to 3 of 3 for “"selectins"”.
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The role of NK cells in selectin-dependent tumor suppression
Selectins are a small family of adhesion molecules that are critical for immune cell trafficking. In our laboratory, mice lacking all combinations of selectins have been generated. Previous work from our laboratory has demonstrated that, in the absence of selectins, human tumors transplanted …
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Einfluss der Inhalationsanästhetika Sevofluran und Desfluran auf die Ausbildung von Adhäsionsmolekülen auf Granulozyten in vitro
… is a multistep process involving several selectins and b2- integrins. Therefore, we assessed wether sevoflurane and desflurane affect the activation of the selectins PSGL-1 (CD162) and L-selectin (CD62L) and the b2- integrins CD11a and CD11b. Whole blood was incubated for 60 minutes with 1 …
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The Role of Glycoconjugates in Mediating Human Fertilization and Induction of Fetomaternal Tolerance
… inhibit immune cell interactions mediated by the selectins, potently block human sperm-egg binding. The selectin ligand sialyl Lewis<sup>x</sup> inhibits sperm binding in the HZA by 60% at a concentration of 1 mg/ml. Our data indicates that glycodelin-A, a endometrial glycoprotein known to block …