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Showing 1 to 1 of 1 for “"secretory lysosome"”.

  1. A novel principle for immunomodulator delivery with hematopoietic cells as vehicles Focus on soluble TNF-receptor gene expression, targeting to secretory lysosomes and regulated secretion

    … from the trans-Golgi network (TGN) to secretory lysosomes, followed by generation of membrane-free soluble sTNFR1. The secretion of sTNFR1 could be triggered by a calcium-ionophore or by crosslinking of the IgE receptors on mast cells leading to degranulation. In contrast, …

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