Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"secondary lymphoid tissues"”.
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Compartmentalization of HIV-1 in the Secondary Lymphoid Tissues
Follicular dendritic cells (FDCs) reside in the lymphoid follicles of the secondary lymphoid tissues (sLTs). Following the infection of an individual with human immunodeficiency virus type 1 (HIV-1), viral particles are trapped in massive quantities on the surfaces of FDCs. HIV-1 viral compartments …
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Of Mice and Men: Studying Innate and Adaptive Immunity Against the Epstein-Barr Virus
… NK cells, which are enriched in human secondary lymphoid tissues, responded primarily to this DC activation. In fact, 100-fold less tonsilar than peripheral blood NK cells were required to achieve the same protection against EBV-mediated B cell transformation in vitro, indicating that …
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A novel antigen-receptor signalling reporter mouse reveals clonotype-independent intratumoral trapping as a spatial feature of CD8+ T cell exhaustion
… in both spatial compartments of the tumour and secondary lymphoid tissues may contain identical clonotypes, I set out to develop workflows that link the selectivity of the AgRSR mouse to in-depth analysis of their transcriptome and clonality using single cell RNA sequencing (scRNAseq) to enable …
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Assessment of Gamma/Delta T Cell Functionality Following Pathogenic HIV/SIV and Non-Pathogenic SIV Infections
… the levels of gamma delta T cells at mucosal and lymphoid sites in macaques utilizing quantitative PCR. At two days post-infection, a decrease in gamma delta T cell levels was observed at mucosa sites whereas increased levels were present at regional lymph nodes. Also, an increase in lymphoid …
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Effect of pomegranate extracts on apoptosis and cell cycle in haematological malignancies.
… of these cells within the bone marrow (BM) and secondary lymphoid tissues. The exact cause of leukaemia remains unknown. Leukaemia is a major problem worldwide affecting many people each year. However, current treatment options still have several limitations not least, the cytotoxicity of these …
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UNVEILING HUMAN NATURAL KILLER CELLS ONTOGENESIS IN HOMEOSTATIC CONDITIONS AND DURING THE IMMUNE RECONSTITUTION AFTER HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION
… cells have been grouped in the family of innate lymphoid cells (ILCs), a recently identified heterogeneous cell population now divided into cytotoxic, by means of NK cells, and helper ILCs, further subdivided in subclusters mimicking helper T cells. Despite advances in the classification of ILCs, …