Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 149 for “"second-harmonic generation"”.
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Second harmonic generation in novel optical waveguides
Second Harmonic Generation has traditionally been restricted to crystals; however, due to the development of highly sophisticated fabrication technology, poling and phase matching techniques, it has now become feasible in glass fibres and waveguides which are widely used in nonlinear optics. For …
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Generation of squeezed light via second harmonic generation
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1994.
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Terahertz Second-Harmonic Generation in Extreme-Confinement Cavities
… coherent radiation spanning the THz gap by second-harmonic generation (SHG) in low-loss dielectric structures, starting from the ∼100 GHz range. For this purpose, we present hybrid THz-band dielectric cavity designs that combine (1) nonlinear materials enhanced by phonon resonances with (2) …
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Second Harmonic Generation – A Novel Approach in Retinal Imaging
<p>Here we present the utilization of Second Harmonic Generation (SHG) for label-free imaging of microtubules (MTs) in the retinal nerve fiber layer (RNFL). MTs are an important part of axonal cytoskeleton, providing structural support and serving as a railroad in intracellular transport. We …
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Mueller-matrix-based analysis for second-harmonic generation imaging
Second-harmonic generation microscopy takes advantage of second-order nonlinear property for imaging of biological structures. Invoking quantitative image analysis techniques facilitates the assessment of tissues in varying states. This thesis presents a quantitative description of the relative …
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Application of beam shaping in second-harmonic generation microscopy
Second-harmonic generation (SHG) microscopy, based on the second-order nonlinear susceptibility, has been established as a sub-micrometer resolution, label-free optical imaging method. Due to its selectivity for non-centrosymmetric structures and inherent confocality, SHG imaging has been used to …
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Wide-field Polarimetric Second Harmonic Generation Microscopy for Histology Imaging
… provides several contrast mechanisms including second harmonic generation (SHG), third harmonic generation (THG) and multiphoton excitation fluorescence (MPEF) that can contribute with additional information to hematoxylin and eosin (H&E) stained tissue histopathology, which is used as a gold …
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UNDERSTANDING AND EVALUATING CRYSTAL POLYMORPHISM BY SECOND HARMONIC GENERATION MICROSCOPY
… factor to trap the rare metastable polymorphs. Second harmonic generation microscopy (SHG) possesses enough sensitivity to detect sub-micrometer size chiral crystals selectively and has the potential for use in crystal nucleation studies.
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Application of quantitative second-harmonic generation imaging to dynamic systems
… is to report the development of a quantitative second harmonic generation technique that quantifies the 2 dimensional spatial orientation of collagen fiber samples under dynamic conditions. The technique is demonstrated both for a well aligned tendon sample and a randomly aligned, sparsely …
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Surfactant dynamics at interfaces : a series of second harmonic generation experiments
… it assumes reorientation dynamics in the millisecond time regime. In order to assess this model, we designed a SHG pump-probe experiment that addresses the orientation dynamics. Results obtained reveal that the orientation dynamics occur in the picosecond time regime, being in strong …
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Identification of quantitative second-harmonic generation imaging metrics for collagenous tissue
Second-harmonic generation (SHG) imaging has high specificity to collagen, sub-micrometer resolution, and optical sectioning capability. It is applied to various unstained collagenous specimens to explore the microstructure. Since collagen is one of the most abundant proteins in biological tissue, …
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Quantifying collagen-based biological tissues using Fourier-transform-second-harmonic generation imaging
… report the generalization of Fourier transform-second-harmonic generation (FT-SHG) imaging to quantify the arrangement of collagen fibers in biological tissues in 3D. Collagen is the primary structural protein in the human body. Depending on the spatial arrangement of collagen fibers, …
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Second-harmonic generation-based Mueller matrix polarization analysis of collagen-rich tissues
… of the cell and its surrounding matrix. Second-harmonic generation (SHG) microscopy is especially well-suited as an image acquisition technique, due to its specificity to the non-centrosymmetric structure of collagen, and inherent confocality which enables three-dimensional sectioning. …
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Second Harmonic Generation in Silicon Photonic Crystal Resonators for Quantum Optic Applications
… photonic crystal nanobeam cavity for efficient second harmonic generation.
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Tissue spectroscopic characterization based on fluorescence, second harmonic generation, and reflected light
… imaging, tri-modal imaging, and interferometric second harmonic imaging. First, two-photon spectral resolved microscopy utilizes the 3D localization ability of two-photon excitation to extract spectroscopic information from a femtoliter volume in tissue. The method is capable of the …
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Coupling qualitative and quantitative analyses of pharmaceutical materials enabled by second harmonic generation microscopy
… stability, and efficacy of a drug product. Second harmonic generation (SHG) microscopy has recently been developed as a selective and rapid method for imaging crystallinity in drug formulations. While SHG microscopy can enable the high signal-to-noise (SNR) detection of crystallinity, the …
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LASER DIODE PUMPED ND: YAG SOLID STATE LASER FOR APPLICATIONS IN SECOND HARMONIC GENERATION
… The application of the ES-pumped YAG laser in second harmonic generation(SHG) is investigated by using a KTP crystal. For Type II SHG of KTP, the phase matching angles and the relative entrance angle of polarized direction of the Q-switch YAG laser are calculated as follows: ?=90°, ?=23.5° and …
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Probing Interfacial Potential under Transient Conditions via Second Harmonic Generation at Pt-water interface
… In this thesis, an optical method based on second harmonic generation (SHG) spectroscopy is used to monitor the electrochemical potential at the platinum (Pt)–water interface during a potential sweep. The results are compared to the constant potential baseline. We observe the deviation …
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Morphological Features of Dysplastic Progression in Epithelium: Quantification of Cytological, Microendoscopic, and Second Harmonic Generation Images
… and an additional shape parameter in second harmonic generation images of label-free freshly resected murine epithelium. Murine models of colorectal cancer (CRC) were imaged at early and late stages of tumor progression, and we noted significant differences between the Control groups …
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Bismuth-, Tin-, and Lead-Containing Metal-Organic Materials: Synthesis, Structure, Photoluminescence, Second Harmonic Generation, and Ferroelectric Properties
… for non-linear optical properties (such as second harmonic generation) and ferroelectric applications.</p> <p>This thesis is divided into two main parts: materials with optical properties, such as photoluminescence and materials for targeted applications such as second harmonic generation …
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