Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"sciatic nerve injury"”.
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The role of ErbB inhibitors in promoting nerve regeneration in a mouse model of nerve injury
Nerve injury is a common clinical challenge that has a considerable impact on an individual’s quality of life and function. Despite multiple surgical strategies, functional outcomes following nerve injury remain poor. Increasing the rate at which axons regenerate could profoundly improve the …
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The Expression Profile of A Gwas Detected Gene (Ninj2) In The Brain of A Mouse Model of Ischemic Stroke
… These SNPs are located 11 Kb upstream of the nerve injury-induced gene 2, Ninjurin2 (NINJ2), suggesting that this gene may be involved in stroke pathogenesis. NINJ2 is a cell adhesion molecule induced in the distal glial cells from a sciatic-nerve injury at 7-days after injury. In an effort to …
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Expression and Requirement of Epithelial Fatty Acid- Binding Protein in Neuronal Axon Growth
… expressed in the dorsal root ganglia following sciatic nerve injury and in migrating and differentiating neurons during neuronal development. It was hypothesized that E-FABP expression is required for the robust outgrowth of axons from developing and regenerating neurons. To test this …
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Calcium signalling in the nervous system
… those belonging to the central and peripheral nerve system. Free intracellular Ca2+ ([Ca2+]i) in resting cells is maintained at low concentrations (submicromolar range). In contrast, the Ca2+ concentration in the extracellular space and the endoplasmic lumen exceeds the 103 - 106 range. This …
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Retinoic acid signalling after peripheral nerve injury
Although the problem of nerve regeneration has been studied since the beginning of the 20th century, the molecular mechanisms of this process are still largely unknown. Recently, the involvement of retinoic acid (RA) signalling was also proposed to regulate PNS regeneration based on its regulation …
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Effects of electrical stimulation and testosterone on regeneration-associated gene expression and functional recovery in a rat model of sciatic nerve crush injury
… is often suboptimal following peripheral nerve injury (PNI). Research to date indicates that the greatest success in achieving full functional recovery will require the use of a combinatorial approach that can simultaneously target different aspects of the post-injury response. In general, …