Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 74 for “"sciatic"”.
-
Development of Collateral Circulation in Partially Devascularized Feline Sciatic Nerve
A survey of the existing literature in the field of peripheral nerve vascularity has established that nerve function is influenced by vascular supply; however, opinion varies considerably concerning the extent of such dependence. Apparently, influence of vascular supply is unquestioned; its …
-
Somatosensory Map Following Stimulation of Rat Sciatic Nerve Using Polyimide Microfabricated Sieve Electrodes
<p>Neural interfaces operate at the intersection of biology and electronics. Development of these interfaces has focused on making it possible to systematically extract intention from cortical activity, to actuate anything from prostheses to computer-assisted communication systems, primarily …
-
Characterization of Materials Carried by Fast Axoplasmic Transport in Sensory Fibers of the Rat Sciatic Nerve
Made available in DSpace on 2014-12-14T04:27:34Z (GMT). No. of bitstreams: 1 7606737.pdf: 5673432 bytes, checksum: b1b066647f754ac528f98825477918ff (MD5) Previous issue date: 1975
-
Characterization of the high frequency alternating current block in the rat sciatic nerve using cuff electrodes and macro-sieve electrodes
… fabricated and non-chronically implanted in the sciatic nerve of two-month-old Lewis rats. A proximal constant current stimulus to the nerve was blocked by applying a high frequency sinusoidal signal to the distally placed tripolar cuff electrode. The frequency voltage characteristic of the …
-
The vascular variability of the iliac system and clinical diagnosis in radiology and neurology
The sciatic nerve is the largest nerve in the human body giving both<br/>motor and sensory innervations to the lower limb. It can be affected in chronic<br/>diseases, such as diabetes, or compressed anatomically by structures such as<br/>piriformis and aneurysms leading to sciatica or paralysis of …
-
Effects of electrical stimulation and testosterone on regeneration-associated gene expression and functional recovery in a rat model of sciatic nerve crush injury
… on functional recovery after crush injury to the sciatic nerve, a mixed sensory and motor spinal nerve which is one of the most serious PNI clinical problems. The results of the present study indicate that either treatment alone or in combination positively impact motor recovery. With regard to …
-
The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: a reversible deactivation study
… the primary motor cortex, spinal cord, and sciatic nerve, are incompletely known. This study aims to consider each of these to develop a better understanding of how spinal cord reflexes and the relationship between the central and peripheral nervous systems, particularly in terms of motor …
-
The Role of Slit/Robo Signalling in Peripheral Nerve Regeneration
… was carried out on both mouse adult intact sciatic nerves and transected sciatic nerves. To establish the role of Slit/Robo during peripheral nerve regeneration, Slit/Robo mutant mice underwent a sciatic nerve transection to replicate a peripheral nerve injury; nerves were removed and …
-
Effects of Electrical Stimulation and Testosterone in Translational Models of Peripheral Nerve Injury
… recovery in two types of injury to the sciatic nerve with or without ES plus TP. The sciatic crush injury was compared to a surgery mimicking an autograft procedure of the sciatic nerve (double transection-repair). Adult male rats were divided into four experimental groups: sciatic …
-
Steroid Hormone and Growth Factor Regulation of Peripheral Myelination
… Lower levels of P0 were found in the developing sciatic nerve of PDGF-A null transgenic mice, especially when active myelin synthesis occurs. Morphological deformities of the myelin sheath were also observed in the sciatic nerve of the null mice. Furthermore, cocultures established with DRG …
-
Neuromuscular Dysfunction as a Novel Indicator for Alzheimer's Disease and Response to Intervention in the 5xFAD Model
… neuromuscular function in both muscle and the sciatic nerve, and exercise adaptations (mitochondrial respiration and RNA sequencing) before overt cognitive impairment. We found that 5xFAD mice develop neuromuscular dysfunction as early as 4 months of age, characterized by impaired nerve- …
-
Growth Factor Delivery From Fibrin Matrics Containing Affinity-Based Delivery Systems To Treat Peripheral Nerve Injury
… in vivo to promote nerve regeneration in a rat sciatic nerve critical defect was determined through histomorphometric outcomes. The ABDS with any affinity peptide and NGF was similar to the isograft in aspects of nerve regeneration including: fiber density, nerve regeneration quality, fiber …
-
Neuroprotective Potential of a Lanosteryl Triterpene from Protorhus longifolia Stem Bark (Benrh.) Engl in high fat diet fed and STZ -induced diabetic neuropathy in rats
… all rats were euthanized and blood (serum), sciatic nerve and brain tissues were collected for analysis of biochemical parameters. v The in vitro results revealed the anti-protein glycation potential of RA-3, accompanied by reduced fructosamine content and enhanced protection of protein thiol …
-
THE ROLE OF SKELETAL MUSCLE-SYNTHESIZED BRAIN DERIVED NEUROTROPHIC FACTOR IN THE MAINTENANCE OF MOTOR NEURON MITOCHONDRIAL POPULATIONS
… groups underwent a gastrocnemius harvest or a sciatic nerve ligation protocol prior to sacrifice. In combination with MitoTracker™ injections, we used immunohistochemical labeling to target the mitochondrial translocase of outer membrane, TOM20. We used immunolabeling to further delineate …
-
Repeatable and adjustable on-demand local anesthesia using externally-triggerable liposomes
… upon insonation 1 MHz, 3W/cm² ultrasound. Sciatic nerve blockades for up to a duration of 2h was successfully achieved with safe dosage of light (730 nm, 75 mW/cm², 15 min) or ultrasound (1 MHz, 3W/cm², 10 min). Sciatic nerve block could be triggered repeatedly with light or ultrasound for …
-
Implementation of Novel Group Delay Decomposition Method and Surgical Protocol for Assessing Peripheral Neuropathy
… procedure for exposing and stimulating the sciatic nerve of an anesthetized rodent for purposes of obtaining conduction velocity readings. The ability to accurately quantify nerve conduction velocity has potential for use in the field of diagnostic medicine and disease characterization. An …
-
Electrochemical Modulation of Peripheral Nerves Using Ion-Selective Electrodes
… operations, implanted in vivo on the sciatic nerve of a rat. I discovered over-limiting phenomena that arise in ISM systems under electrical polarization, which have broad implications for all of its ion filtering applications. Finally, from my electrophysiological studies, I found …
-
Pilot Study Exploring the Effect of Targeted COX-2 Inhibition in Macrophages Responding to Neuronal Injury; Promoting Enhanced Axonal Regeneration
… have peripheral nerve injury constricting the sciatic nerve relieves hypersensitivity, a pain-like behavior. The treatment also decreases inflammation associated with this chronic constriction injury (Janjic et al, 2018; Saleem et al, 2019b; Stevens et al, 2019). In this project, we evaluated …
-
Development and Applications of Opioids Alternatives for Pain Management
… of the hydrogel/TTX formulation produced a sciatic nerve block lasting up to 10 hours.Despite progress, the duration of nerve blockade remains insufficient for clinical needs. The physical encapsulation method limits TTX dosage due to unstable release kinetics. Therefore, polymer-TTX …
Page 1 of 4