Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"scavenger receptors"”.
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Studies of the Class A and Class C scavenger receptors
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1997.
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Structure and function of a class A macrophage scavenger receptors
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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Role of scavenger receptor MARCO in particle uptake and lung inflammation
… the role of membrane glycoproteins called scavenger receptors in binding of environmental particles. The scavenger receptors are classified into different classes (A-H) based on their structure and function. Class A scavenger receptors are critical in uptake of variety of ligands such as …
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Role of scavenger receptor MARCO in particle uptake and lung inflammation
… the role of membrane glycoproteins called scavenger receptors in binding of environmental particles. The scavenger receptors are classified into different classes (A-H) based on their structure and function. Class A scavenger receptors are critical in uptake of variety of ligands such as …
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Reversal of Neurodegeneration By Engineered Monocytes In Alzheimer’S Disease
… neurotoxic inflammation. In tumor immunity, scavenger receptors such as CD163, CD204 and FcRIIb act to limit the proinflammatory responses of the myeloid stroma. We sought to repurpose this system to facilitate o-Tau internalization in AD while limiting inflammation. Unlike microglia in late …
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Receptor-dependent phagocytosis of <i>Clostridium sordellii</i> by human decidual macrophages
… the hypothesis that human DMs utilize class A scavenger receptors (CASRs) to internalize unopsonized C. sordellii. In vitro phagocytosis assays with human DMs incubated with pharmacological inhibitors of CASRs (fucoidan, polyinosinic acid, and dextran sulfate) revealed a role for these …
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Molecular Response of Retinal Pigment Epithelial Cells to Oxidized Lipoproteins: Global and Targeted Studies
… in ARPE-19 cells.</p> <p>We studied the role of scavenger receptors CD36 and CD5L/AIM in ARPE-19 cells when induced with oxLDL. We compared three different multidimensional proteome fractionation platforms: polymeric reversed-phase liquid chromatography at high pH (PLRP), sodium dodecyl …
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Seeing Inside a Concussion: The Role of Microglia in Maintaining the Blood-Brain Barrier in Repetitive Mild Traumatic Brain Injury
… dependent on purinergic pathways and microglial scavenger receptors. We also performed single-cell analysis to further dissect whether there exist separate populations of microglia that perform distinct roles following repetitive brain injury. Our results demonstrate that microglia play a …
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Lysophosphatidylcholine acyltransferase-2 (LPCAT-2) & protein S-acylation in macrophage innate immunity
… blot analysis confirmed the acylation of the scavenger receptors CD36 and Lysosome membrane protein II. Further investigation established that CD36 positively regulates LPS induced cytokine responses in macrophages and that S-acylation of CD36 regulates both lipid raft association and surface …
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Candida Albicans Als5p Amyloid In Host-Microbe Interactions: A Ceanorhabditis Elegans Study
… innate immune system of the nematode. Toll- Like receptors (TLRs) are important mediators of innate immune responses to Candida albicans, and several classes of scavenger receptors have been implicated in recognizing and reacting to a variety of ligands in humans[4]. The C. elegans genome encodes …
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Pathogenesis of experimental tuberculosis in guinea pigs
… accompanied by increased expression of the OxLDL scavenger receptors CD36 and LOX-1. The significance of these data are that through the use of the guinea pig tuberculosis model, we have uncovered a previously unrecognized mechanism by which the host and pathogen interact to create a unique …