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Showing 1 to 20 of 41 for “"scavenger receptor"”.

  1. Role of scavenger receptor MARCO in particle uptake and lung inflammation

    Thakur, Sheetal A.

    … the role of membrane glycoproteins called scavenger receptors in binding of environmental particles. The scavenger receptors are classified into different classes (A-H) based on their structure and function. Class A scavenger receptors are critical in uptake of variety of ligands such as …

    montana-tech Repository record

  2. Role of scavenger receptor MARCO in particle uptake and lung inflammation

    Thakur, Sheetal A.

    … the role of membrane glycoproteins called scavenger receptors in binding of environmental particles. The scavenger receptors are classified into different classes (A-H) based on their structure and function. Class A scavenger receptors are critical in uptake of variety of ligands such as …

    montana Repository record

  3. The role of scavenger receptor B-I in hepatitis C virus attachment and entry.

    Grove, JosephUniversity of Birmingham2009

    … on at least three cellular entry factors: CD81, Scavenger Receptor B-I (SR-BI) and Claudin-1. SR-BI is a receptor for high density lipoprotein (HDL), it is predominantly expressed in the liver and steroidogenic tissue. HCV is believed to interact with SR-BI via the viral envelope protein E2, …

    birmingham Repository record

  4. Tissue specific regulation of the high density lipoprotein (HDL) receptor, scavenger receptor Class B, Type I (SR-BI) by the scaffold protein PDZK1

    Fenske, Sara AnneMassachusetts Institute of Technology2008

    … Cterminus of the high-density lipoprotein (HDL) receptor SR-BI. Abolishing PDZK1 expression in PDZK1 knockout (KO) mice leads to a post-transcriptional, tissue-specific decrease in SR-BI protein level and an increase in total plasma cholesterol carried in abnormally-large HDL particles. A greater …

    mit Repository record

  5. The influence of oxidised low density lipoproteins on platelet activation

    Wraith, Katie SuzanneHull York Medical School, the University of Hull and the University of York2013

    … activating platelets through G protein coupled receptors stimulate MLCSer¹⁹ phosphorylation by the activation of dual pathways that lead to a Ca²⁺ dependent activation of MLC kinase (MLCK) and the Rho kinase dependent inhibition of MLC phosphatase (MLCP). OxLDL induced platelet shape change …

    hull Repository record

  6. Potential Modifications to Enzyme Replacement Therapy in Anderson-Fabry Disease

    Meghdari, MariamThe Graduate School and University Center of The City University of New York2019

    … on targeting of αGal to the very high uptake scavenger receptor (SR) for improved transport to the lysosome.</p>

    cuny-grad Repository record

  7. Candida Albicans Als5p Amyloid In Host-Microbe Interactions: A Ceanorhabditis Elegans Study

    Bois, MichaelThe Graduate School and University Center of The City University of New York2016

    … innate immune system of the nematode. Toll- Like receptors (TLRs) are important mediators of innate immune responses to Candida albicans, and several classes of scavenger receptors have been implicated in recognizing and reacting to a variety of ligands in humans[4]. The C. elegans genome encodes …

    cuny-grad Repository record

  8. Analysis of the function and subcellular localization of FAT/CD36 in hepatocytes and transfected cell lines of hepatic and non-hepatic origin.

    Eyre, Nicholas Stratford2007

    The class B scavenger receptor CD36, or fatty acid translocase (FAT), is an 88 kDa plasma membrane glycoprotein that is the founding member of the class B scavenger receptor family. It has a number of natural ligands and has different functions at various locations in the body. It contributes to …

    adelaide Repository record

  9. Monocyte Modulation of Disease Pathogenesis and Progression in Localized Aggressive Periodontitis

    Shin, Chu Ri2014

    … the differential expression and function of the scavenger receptor CD36. LAgP monocytes have exhibited decreased activity of the PAF-acetylhydrolase (PAFAH), the catalytic enzyme that breaks down PAF. Since PAF levels are regulated by synthesis and degradation, we hypothesized that synthesis by …

    vcu Repository record

  10. Analysis of genetic variation in Pediculus humanus and Populus trichocarpa

    Olds, BrettUniversity of Illinois at Urbana-Champaign2013

    … Serpin (PHUM311330), Cactus (PHUM345810), Scavenger receptor A (ScavA; PHUM066640) and Apolipoprotein D (PHUM427700). Increased expression of Fibrinogen-related protein and Spaetzle, both related to the Toll pathway, in treated body lice supports the hypothesis that body lice are fighting …

    uiuc Repository record

  11. Molecular Basis of HDL-Mediated Endothelial Cell Migration and Reendothelialization

    Seetharam, Divya2010

    … vitro in a nitric oxide-independent manner via scavenger receptor B type I (SR-BI)-mediated activation of Rac GTPase. This process does not require HDL cargo molecules, and it is dependent on the activation of Src kinases, phosphatidylinositol 3-kinase, and p44/42 mitogen-activated protein …

    utswmed Repository record

  12. CHOLESTEROL ABSORPTION AND TRANSINTESTINAL CHOLESTEROL EFFLUX (TICE) RATES ARE UNALTERED IN MICE OVEREXPRESSING INTESTINAL SR-BI.

    Bura, Kanwardeep SinghWake Forest University2011

    … regulating TICE. It has long been known that scavenger receptor class B type I (SR-BI) plays a crucial role in RCT in the liver by facilitating selective uptake of high density lipoprotein (HDL) cholesterol. Interestingly, SR-BI is also expressed in the small intestine. Previously it has been …

    wfu Repository record

  13. Crosstalk between CX3CL1 and the Cytoskeleton during Vascular Inflammation

    Wong, Harikesh2016

    … the lateral diffusion and clustering of the scavenger receptor CD36. Consequently, CD36 more readily engages and internalizes cholesterol-rich, oxidized low-density lipoproteins, leading to the accumulation of cholesterol esters within macrophages, and thus, the acceleration of foam cell …

    toronto-retro Repository record

  14. Defining the mechanism(s) of Hepatitis C virus (HCV) entry

    Schwarz, Anne-KatrinUniversity of Birmingham2009

    … clathrin- and pH-dependent, and requires CD81, Scavenger receptor BI (SR-BI), and the tight junction (TJ) proteins Claudin-1 and Occludin. Primary HCV strains cannot be efficiently cultured in vitro, making the evaluation of potential antiviral compounds in a biologically relevant context …

    birmingham Repository record

  15. Characterising the role of haptoglobin in experimental subarachnoid haemorrhage.

    Morris, Thomas Craig2015

    … CSF Hp and soluble CD163 macrophage haemoglobin scavenger receptor from baseline, concomitant with the Hb peak at the 24hr mark, with a steady and rapid taper off, in keeping with clearance of free Hb by 72hrs post-SAH. Additionally, histological assessment to examine macrophage receptor for …

    adelaide Repository record

  16. Role of SFLT-1 in vascular regulation in pregnancy and its effect on fetal vascular programming

    Fangxian LuThe University of Texas Medical Branch2009

    … inhibition of these factors by a circulating scavenger receptor, soluble VEGFR-1, also called sFlt-1, is believed to play a role in the pathogenesis of preeclampsia. \r\nWe created a mouse model of preeclampsia induced by administration of adenovirus carrying sFlt-1. We have shown that …

    utmb Repository record

  17. Dissecting the Entry Pathways of Hepatitis C and Bovine Viral Diarrhea Viruses

    Tscherne, Donna M

    … to entry was shown to occur downstream of CD46 receptor expression and BVDV binding, suggesting interference with a yet unidentified BVDV entry factor. In contrast to BVDV, HCV-infected and replicon-containing cells exhibit a post-entry block to superinfection, at one or more steps in viral …

    rockefeller Repository record

  18. Mode of Entry and Survival of Salmonella Enterica Serovar Typhimurium in Trophoblast Cells

    Nguyen, TinaUniversité d'Ottawa / University of Ottawa2017

    … placental choriocarcinoma cell lines through scavenger receptor-mediated endocytosis. Next, we observed that S.Tm failed to grow vigorously in macrophages, but replicated rapidly within epithelial and placental trophoblast cells. Further examination of intracellular localization of S.Tm …

    ottawa-retro Repository record

  19. Mining Genomic Variants And Causal Pathways Linking Hdl And Triglycerides To Coronary Disease

    Khetarpal, Sumeet Anand2016

    … (LOF) variant in SCARB1, which encodes scavenger receptor class BI (SR-BI), a hepatic receptor for HDL-C. Despite markedly elevated HDL-C, carriers of this variant had an increased risk of CHD. These findings suggest that HDL functionality in driving cholesterol removal through SR-BI …

    penn Repository record

  20. The Role of Silicates in Interstitial Lung Disease

    Leyva, Francisco Jose

    … Prostacyclin release was Cox 2 and vitronectin receptor (VNR) mediated. Coating crocidolite asbestos with vitronectin enhances its internalization via VNR, which also recognize the Arg-Gly-Asp (RGD) motif present in a variety of ligands (e.g., vitronectin, fibronectin). These findings propose …

    montana-tech Repository record

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