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Showing 1 to 12 of 12 for “"saxitoxin"”.

  1. Tritiated Saxitoxin Binding in the Vertebrate Heart

    Tanaka, Jacqueline CreeksUniversity of Illinois at Urbana-Champaign2014

    Labelled toxins such as ('3)H-STX which selectively bind to the sodium channel have been used to estimate the density of channels on the membrane. While many biochemical investigations of excitable tissues have been made on nerve, skeletal muscle or electric organ with ('3)H-STX, relatively little …

    uiuc Repository record

  2. The effect of the cyanobacterial toxin saxitoxin on neurodevelopment

    O’Neill, Katie2017

    The potent neurotoxin saxitoxin (STX) belongs to a group of structurally related analogues, collectively known as the paralytic shellfish toxins, produced by both marine and freshwater phytoplankton. This group of toxins act by blocking the voltage-gated sodium channels, halting the inflow of …

    adelaide Repository record

  3. A Putative Cytosolic Saxitoxin Binding Protein in Frog Myocardium

    Doyle, Donald DavidUniversity of Illinois at Urbana-Champaign2014

    … are found in F1 respectively. Total binding of Saxitoxin (STX), a Na('+)-channel specific neurotoxin, is only 25% retained, 6% in F1. Total 5'-nucleotidase activity is only 5% retained, less than 1% in F1. Sugar containing proteins detectable by periodic acid-Schiff base (PAS) staining of …

    uiuc Repository record

  4. Tritiated Saxitoxin Binding to Whole Frog Heart and Frog Heart Homogenates

    Wong, MartinUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-12-14T05:40:44Z (GMT). No. of bitstreams: 1 7915447.pdf: 5297036 bytes, checksum: 11db52c4a4fd8549a25f458ce8122b34 (MD5) Previous issue date: 1979

    uiuc Repository record

  5. Cell cycle dynamics and the physiology of saxitoxin biosynthesis in Alexandrium fundyense (Dinophyceae)

    Taroncher-Oldenburg, GasparMassachusetts Institute of Technology and Woods Hole Oceanographic Institution1998

    The mechanism of saxitoxin (STX) biosynthesis in marine dinoflagellates of the genus Alexandrium is still unknown. The aim of this thesis was to analyze novel aspects of toxigenesis during the cell cycle in Alexandrium and to apply molecular techniques to gain new insights on the genetics and …

    woods-hole Repository record

  6. Cell cycle dynamics and the physiology of saxitoxin biosynthesis in Alexandrium fundyense (dinophyceae)

    Taroncher Oldenburg, Gaspar, 1968-Massachusetts Institute of Technology1998

    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.

    mit Repository record

  7. A STUDY OF BIOCHEMICAL MECHANISMS INVOLVED IN THE NEUROMUSCULAR BLOCKING ACTIVITIES OF SAXITOXIN AND TETRODOTOXIN

    HOPKINS, ELWOOD WILBUR, III.

    unh-thes Repository record

  8. Phenotypic diversity within two toxic dinoflagellate genera : environmental and transcriptomic studies of species diversity in Alexandrium and Gambierdiscus

    Pitz, KathleenMassachusetts Institute of Technology and Woods Hole Oceanographic Institution2016

    … is a planktonic species that produces saxitoxins that can directly accumulate in shellfish and cause paralytic shellfish poisoning (PSP) in humans. Both genera contain multiple species that vary dramatically in toxicity and physiology. Through transcriptomic analysis, this thesis …

    woods-hole Repository record

  9. Phenotypic diversity within two toxic dinoflagellate genera : environmental and transcriptomic studies of species diversity in alexandrium and gambierdiscus

    Pitz, Kathleen JohnsonMassachusetts Institute of Technology2016

    … is a planktonic species that produces saxitoxins that can directly accumulate in shellfish and cause paralytic shellfish poisoning (PSP) in humans. Both genera contain multiple species that vary dramatically in toxicity and physiology. Through transcriptomic analysis, this thesis …

    mit Repository record

  10. The competitive dynamics of toxic and non-toxic ribotypes of the harmful dinoflagellate Alexandrium tamarense in Scottish waters

    Eckford-Soper, LisaUniversity of Edinburgh2013

    … previous research studies, have shown that the saxitoxin producing (Group I) and, recently, the non-saxitoxin producing (Group III) ribotypes of Alexandrium tamarense are present in Scottish waters, co-occurring in some locations. Shellfish toxicity events may have been in decline in recent …

    uhi-uk Repository record

  11. A Promiscuous Path to Novel Guanidines: Arginine-Modifying Enzymes as Key Synthetic Players

    Fakhry, Ayman A.A.University of Bradford2026

    … the flexibility of the early enzymes involved in saxitoxin biosynthesis and the engineerability of the pathway for producing novel saxitoxins with therapeutic and mechanistic enzymology potential.

    bradford Repository record

  12. An Evaluation of the risks to food safety and shellfish farming in Great Britain,posed by marine biotoxins from, current and future emerging, marine microalgal species

    Lewis, AdamUniversity of Westminster2024

    … allowing for separation of two key GB saxitoxin producers, A. minutum and Alexandrium catenella. This technique could enhance routine monitoring data with little additional cost. Assessment of harmful microalgal taxa considered as non-native species (NNS) to GB suggested that several …

    westminster Repository record