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Showing 1 to 1 of 1 for “"sapatinib"”.

  1. Resistance to HER2-targeted therapies in HER2-positive breast cancer

    … resistance to the HER2-targeted therapy, sapatinib, and to characterise and validate tumours from a sapatinib-treated spontaneous mouse model of HER2-positive breast cancer. The EMT-linked transcription factor ZEB1 was associated with acquired resistance to sapatinib in tumours that had …

    edinburgh Repository record for Resistance to HER2-targeted therapies in HER2-positive breast cancer (opens in a new tab)