Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"salivary gland"”.
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Diabetes-related ultrastructural and immunohistochemical changes in human salivary gland parenchyma and a study on a native scaffold obtained from salivary gland stroma
… medications, and radiation therapy often affect salivary gland morphology and functionality, giving rise to changes in quantity and composition of saliva and to numerous oral complications that severely compromise the patient’s life quality. The aim of this thesis, articulated into two sections, …
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Significance of Salivary Gland Radioiodine Retention on Post-ablation 131I Scintigraphy as a Predictor of Salivary Gland Dysfunction in Patients with Differentiated Thyroid Carcinoma
… scintigraphy could predict functional changes in salivary glands after radioiodine therapy. METHODS: We evaluated 90 patients who received initial high-dose (≥3.7 GBq) radioiodine therapy after totalthyroidectomy.Allpatients underwent diagnostic (DWS) and post-ablation (TWS) 131I whole-body …
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The role of Wnt signalling during embryonic salivary gland development
… structure that is a characteristic of the salivary glands and other organs including the lungs, kidneys and mammary glands. Branching morphogenesis is the mechanism by which a single epithelial bud undergoes repetitive cycles of bifurcation in order to maximise its surface area within a …
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The role of the P2Y2 nucleotide receptor in salivary gland regeneration
Salivary gland dysfunction affects millions of Americans whose quality of life is severely impacted by dry mouth, oral bacterial infections, poor nutrition, and other disorders that are associated with decreased saliva production. Over the past decade, progress has been made in cell-based …
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Influence of magnesium on salivary gland secretion: physiological and pathophysiological studies
… lachrymal and the parietal cells. Since the salivary glands acinar cells have a similar structure and function as the exocrine pancreas, the stomach and the lachrymal gland, it was decided to investigate specifically the effect of perturbation of extracellular magnesium ([Mg2+]0) on both …
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Exploring the transcriptomic landscape of the Drosophila melanogaster embryonic salivary gland.
… found in the Drosophila melanogaster embryonic salivary gland. Once specified, two mirror-symmetric placodes internalise from a flat epithelium in a coordinated manner, form two narrow-lumen epithelial tubes on the inside and eventually fuse to form a Y-shaped organ. Salivary gland cells do not …
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The Role of Mesenchymal Cells in the Regeneration of Salivary Gland Tissue
… will suffer a variable degree of damage to their salivary glands, caused by lesions of immune infiltrates into the tissue surrounding duct structures. Some patients present with extensive lesions that destroy any residual secretory acinar tissue, leading to hyposalivation. This damage, and reduced …
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Investigating the role of macrophage-epithelial cell interaction in salivary gland regeneration
… dry-mouth), which results from irreversible salivary gland hypofunction. Although xerostomia has a detrimental impact on patient quality of life, there are currently no long-term solutions to restore salivary gland function, and patients have to rely on short-term solutions which currently …
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Human Salivary Gland Stem/Progenitor Cells for Tissue Engineering, SARS-CoV-2 Susceptibility, and Neurointegration
<p>Salivary glands and the saliva they secrete are important for digestion, chewing, and maintaining oral health. Reduced saliva production leads to a decreased quality of life for patients experiencing hyposalivation as a result of disease or injury, thus a large effort has been dedicated to …
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Perineural Invasion in Oral Squamous Cell Carcinoma and Salivary Gland Malignancies: Incidence, Prognostic Impact and Molecular Insight
… (PNI) in oral squamous cell carcinoma (OSCC) and salivary gland malignancies (SGMs) worldwide. PNI exhibited by some OSCC and SGMs has been known as an independent predictor of poor prognosis and an indicator of aggressive behaviour. Furthermore, the literature suggests a possible molecular …
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Surgery on the submandibular salivary gland for anterior and posterior drooling in children and adolescents with neurodevelopmental disorders
Contains fulltext : 311850.pdf (Publisher’s version ) (Open Access)
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A NOVEL MAGNETIC THREE-DIMENSIONAL LEVITATED PRIMARY CELL CULTURE SYSTEM FOR THE DEVELOPMENT OF IN VITRO SALIVARY GLAND-LIKE ORGANOIDS
Salivary gland (SG) hypofunction and dry mouth leads to oral complications and impaired quality of life. Recently, researchers have proposed to repair hypo-functional SG via various cell-based approaches in three-dimensional (3D) scaffold-based systems. The majority have nonhuman-based components. …
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Functional Restoration of Irradiated Salivary Glands Through Modulation of aPKCζ and Nuclear Yap in Salivary Progenitors
… these individuals receive radiation therapy, and salivary hypofunction and xerostomia occur in 60-85% of these patients due to irreversible damage to the salivary glands. Current preventative and palliative care fail to improve quality of life, accentuating the need for regenerative therapies. …
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Tissue-Specific Matrix Control of Cell Cohesion and Migration Signaling Complexes
… healing, and cancer cell metastasis. Using two glandular organs, the normal salivary gland and the cancerous prostate, this dissertation describes the tissue-specific composition of two ECM signaling complexes (type I hemidesmosomes and the perlecan-semaphorin 3A-plexin A1-neuropilin-1 (PSPN) …
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An analysis of the role of microtubules during tubulogenesis in Drosophila
… In this thesis I used the formation of the salivary glands in the Drosophila embryo, which are formed by coordinated apical constriction and invagination of a polarised epithelial placode, as a model to understand these changes. The role of microtubules (MTs) during morphogenetic processes …
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Development of a comprehensive annotation and curation framework for analysis of Glossina Morsitans Morsitans expresses sequence tags
… transcripts differentially expressed in the salivary gland and midgut and provides candidate genes that are critical to response to parasite invasion. Furthermore, an open-source Glossina resource (G-ESTMAP) was developed that provides interactive features and browsing of functional genomics …
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Detection of zoonotic bacterial pathogens in multiple hosts using a microbiome approach and molecular characterization of Anaplasma phagocytophilum
… of the bacterial microbiome from 24 pools of salivary glands and 23 pools of midgut tissues from the 348 A. hebraeum ticks produced a total of 86,308 bacterial sequence reads from the midgut pools as well as 84,420 sequences from the salivary gland pools. Of these, 81.7% of the bacterial …
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Vitellogenesis in <i>Hyalomma dromedarii</i> (Acari: Ixodidae): A Model for Analysis of Endocrine Regulation in Ixodid Ticks
… repletion. The level of vitellogenin in midgut, salivary gland and muscle, increased slowly during repletion, and never exceeded 1.1% of its respective tissue protein.</p> <p>Tissue specific synthesis of vitellogenin and vitellin was monitored <em>in vitro</em>. Continuous synthesis of …
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ΜΕΛΕΤΗ ΤΩΝ ΠΟΛΥΤΑΙΝΙΚΩΝ ΧΡΩΜΟΣΩΜΑΤΩΝ ΤΩΝ ΚΥΤΤΑΡΩΝ ΤΩΝ ΣΙΑΛΟΓΟΝΩΝ ΑΔΕΝΩΝ ΤΗΣ DROSOPHILA AURARIA
… UNIQUE AMONG DROSOPHILA SPECIES IN THAT THEIR SALIVARY GLAND CHROMOSOMES EXHIBIT BALBIANI RING (BRS). WE PRESENT HERE A CYTOLOGICAL MAP OF D. AURARIA AND INFORMATION ON THE DEVELOPMENTAL PROFILES OF ITS PUFFS AND BRS. AUTORADIOGRAPHY HAS BEEN PERFORMED IN ORDER TO CONFIRM THE RNA SYNTHESIS OF …
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