Global ETD Search
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Showing 1 to 2 of 2 for “"salicylidene acylhydrazides"”.
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Identification and characterization of type III secretion inhibitors in Erwinia amylovora, the causal agent of fire blight of apple and pear
… hrp inducing conditions. Five of them belong to salicylidene acylhydrazides. Among them, chemical # 3 and # 9 were most potent in inhibiting T3SS gene expression in a dose-dependent manner without affecting bacterial growth. Furthermore, this group of chemicals also inhibited exopolysaccharide …
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Analysis of Small Molecule Inhibitors Aimed at Bacterial Virulence
… for evaluating an anti-virulence approach. The salicylidene acylhydrazides (SAHs) are a class of compounds that prevent secretion of bacterial effector proteins through the T3SS and attenuate infection from various species of Gram-negative pathogens; however, the molecular target(s) of these …