Global ETD Search

The oligomeric state of archaeal fibrillarin : implications in the organization and function of essential box C/D sRNP particles

Burke, Paula Louise, University of Lethbridge. Faculty of Arts and Science2006

lethbridge

A TALE OF TWO METHYLATION MODIFICATIONS IN ARCHAEAL RNAs

Chatterjee, Kunal2014

… mechanism of target RNA recruitment to a box C/D sRNP. From data obtained, we have made the following hypothesis- aNop5p, either alone or as a heterodimer with Fibrillarin, binds to single stranded bulges and loops of target RNA. This aNop5p bound target is then hybridized to an assembling guide …

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STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF ARCHAEAL BOX H/ACA RIBONUCLEOPROTEIN INVOLVED IN RIBOSOMAL RNA PSEUDOURIDYLATION

MAJUMDER, MRINMOYEE2016

… H/ACA RNA form the ribonucleoprotein complex in sRNP-mediated rRNA pseudouridylation. Certain Ys in rRNAs are evolutionarily conserved from Bacteria to human. Among those, two Ys are present in helix 69 of rRNA and one in helix 90. We successfully deleted Cbf5 in Haloferax volcanii, a …

siu-theses Repository record for STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF ARCHAEAL BOX H/ACA RIBONUCLEOPROTEIN INVOLVED IN RIBOSOMAL RNA PSEUDOURIDYLATION (opens in a new tab)

Multi-domain Protein Unfolding Pathway Studies by Single Molecule Techniques

LI, QING2017

… domain of a natural protein (Archeal Box C/D sRNP Core Protein) to enable us to capture the progress of the unfolding front along the host protein structure. In this way, the structural origin of the signal from single molecule force spectroscopy (SMFS) based on atomic force microscopy (AFM) …

duke Repository record for Multi-domain Protein Unfolding Pathway Studies by Single Molecule Techniques (opens in a new tab)

Construction and initial characterization of yeast strains with Dyskeratosis congenita mutations

Ogailan, Abeer Abdullah, University of Lethbridge. Faculty of Arts and ScienceLethbridge, Alta : University of Lethbridge, Dept. of Chemistry and Biochemistry2017

The effect that Dyskeratosis congenita mutations have on ribosome biogenesis has not been fully investigated. Here, I am studying the effect of Dyskeratosis congenita mutations using a yeast model system with the goal of identifying impacts on ribosome biogenesis. I constructed six haploid yeast …

lethbridge Repository record for Construction and initial characterization of yeast strains with Dyskeratosis congenita mutations (opens in a new tab)

Präparation und röntgenkristallographische Untersuchungen an archaebakteriellen Box C/D sRNPs und einer neuartigen Glukosyltransferase aus Thermotoga maritima MSB8

Steinke, Carmen2012

Ribosomale RNAs werden posttranskriptional durch kleine nukleoläre RNAs (snoRNAs) modifiziert. Dabei kommt es zum einen zur Umwandlung von Uridin in Pseudouridin durch die H/ACA-Box snoRNAs und zum anderen zur 2'-O-Methylierung von Ribose durch Box C/D snoRNAs, wobei beide snoRNA-Familien mit …

goettingen Repository record for Präparation und röntgenkristallographische Untersuchungen an archaebakteriellen Box C/D sRNPs und einer neuartigen Glukosyltransferase aus Thermotoga maritima MSB8 (opens in a new tab)