Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"sFRP2"”.
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Wnt Modulators, Secreted Frizzled Related Protein (sFRP) 2 and Wnt Inhibitory Factor (WIF)-1, Stimulate Melanogenesis in Normal Human Melanocytes
… high levels of frizzled-related protein 2 (sFRP2) and Wnt inhibitory factor-1 (WIF-1) compared to perilesional normal skins. In this study, I investigated the functional roles of sFRP2 and WIF-1 on skin pigmentation. The present study demonstrated that sFRP2 and WIF-1 were expressed in both …
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INTEGRATED MOLECULAR INVESTIGATIONS OF MYRF AND SFRP2: UNVEILING REGULATORY MECHANISMS OF ER STRESS AND ECM REMODELLING IN PANCREATIC CANCER
… Additionally, we focused on the role of SFRP2 as a potential regulator influencing the characteristics of PDAC transitional cells. One of the key aspects of transitional cancer cells is the ability to contribute to the extracellular matrix (ECM) remodeling: we observed that SFRP2 led to a …
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Epigenetic modifications on WNT genes by dietary genistein during colon cancer development
… restored the expression of a Wnt antagonist sFRP2, which was silenced in colon cancer cells, by affecting the DNA methylation at the promoter of the gene. Consequently, the abnormally activated Wnt signaling was attenuated, leading to repressed cancer cell viability and increased apoptosis. …
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Immunohistochemical Evaluation and Gene Expression Profiling of Senile Lentigo
… transcription factor), Ki67, SFRP2 (secreted frizzled-related protein 2), Wnt-5a, p16 and p53 and computer-assisted image analysis were performed. DNA microarray analysis was carried in one female volunteer with both lentigo and melasma. RESULTS: Histological features of senile …
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Identifizierung und Charakterisierung von Genen für die Entwicklung der Nieren und des Urogenitalsystems
… ausgewählt. Als eines der bekannten Gene wurde sFRP2 als im metanephrogenen Mesenchym induziert bestätigt und durch in situ Hybridisierung ganzer Mäuseembryonen und Paraffinschnitte näher untersucht. Es zeigt eine spezifische und dynamische Expression während der Entwicklung der Niere und …