Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"rupture force"”.
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Interaction Forces And Reaction Kinetics Of Ligand-Cell Receptor Systems Using Atomic Force Microscopy
<p>Atomic Force Microscopy (AFM) provides superior imaging resolution and the ability to measure forces at the nanoscale. It is an important tool for studying a wide range of bio-molecular samples from proteins, DNA to living cells. We developed AFM measurement procedures to measure protein …
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Understanding the mechanical strength of microcapsules and their adhesion on fabric surfaces
… mixing, drying etc, but be weak enough to be ruptured by consumers in post-laundry handling. For this purpose, the mechanical strength of MF microcapsules made by different processing conditions, with additional coating, after being dried using different methods and being exposed to various …
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Diffusion related processes in nanoconfined liquids and in proteins under force
… nanopores, and in modeling single molecule forced rupture experiments of biomacromolecules. Based on a method used to calculate the position-dependent diffusion coefficients in inhomogeneous liquids, we apply absorbing boundary conditions in the analysis of molecular dynamics trajectories of …
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Applications of Optical Manipulation for Low Cost Implementation, Beam Shaping and Biophysical Force Measurements
… the ability to quantitively exert and measure forces on the piconewton scale, a convenient force scale for soft biological materials, and are hugely versatile due to the wide assortment of beam shaping techniques that can be employed.<br/><br/>The work in this thesis can be broadly divided into …
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Development of a novel micropipette aspiration-based force sensing technique to measure single cell sliding friction
… and when the cells propagate, the bonds are ruptured at an angle sustained by the cells’ curvature. The presence of tangential force component (or the sliding friction) and the recruitments of auxiliary stress-dependent ligands at the adhesion site mean conventional cell detachment model is …
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Mapping the actin and actin binding proteins interactions : from micromechanics to single molecule force spectroscopy
Mechanical forces play an important role in cell morphology, orientation, migration, adhesion and can even induce apoptosis. The eukaryotic cell is equipped with a dynamic frame, known as the cytoskeleton, that provides the cell's structural integrity in order to sustain and react to such forces. …
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Fracture Mechanics of Networks
… area – of a polymer network is the energy to rupture a layer of chains, they can underestimate experiments by up to two orders of magnitude. In Part I, we show that the intrinsic fracture energy of polymer-like networks stems from nonlocal energy dissipation. We then reveal a general scaling …
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Calcium carbonate biomineralization: A theoretical and experimental investigation of biomolecular controls on nucleation and growth
… with measurements of crystal – substrate rupture force from dynamic force microscopy. These investigations show that an important function of biomolecules in directing mineralization lies in their ability to modulate cation hydration. Both chemical functionality and molecular conformation …
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Investigation of protein-protein interaction using atomic force microscopy
… </p> <p>In our laboratories, we use the force spectroscopy (FS) technique to study protein binding and dissociation. FS measures the strength of the protein molecules bond with high resolution down to pico-Newton either on the surface of solid substrate or the membrane of living cells. …