Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"running wheel"”.
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Self-Control Choices Using Running Reinforcement
… the delivery of a smaller, immediate access to a running wheel (Impulsive) while responding on the other lever resulted in the delivery of larger but delayed access to a running wheel (Self-control). A variable inter-trial-interval was used to control the session duration regardless of the …
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Self-Control Choices Using Running Reinforcement
… the delivery of a smaller, immediate access to a running wheel (Impulsive) while responding on the other lever resulted in the delivery of larger but delayed access to a running wheel (Self-control). A variable inter-trial-interval was used to control the session duration regardless of the …
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The effect of a tryptophan-depleted diet on voluntary exercise in mice
… CW consumed a control diet and had access to a running wheel. Group E received a diet low in tryptophan while group EW was given the experimental diet and had access to a running wheel. A seven-day adaptation period was followed by a ten-day experimental period during which time groups E and EW …
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The Majority of the Diaphragm Immune Transcriptome Profile Rescued in Mdx Mice by Microdystrophin Gene Therapy was maintained by Voluntary Wheel Running
… microdystrophin gene therapy with and without running wheel activity. Mdx mice are a model of Duchenne Muscular Dystrophy (DMD). Similar to DMD, mdx pathophysiology is associated with chronic inflammation due to sarcolemma fragility and cellular membrane leakage. Immune modulation has not yet …
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Pre-Exposure and Recovery in Activity-Based Anorexia
… feeding schedule and pre-exposure to a running wheel on the incidence of ABA in 36 rats. Access to food and the running wheel was also varied in the recovery phase of the study in order to establish the effect of these variables on recovery from ABA. Three adaptation conditions …
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Exercise induced neuroprotection in spontaneuosly running rats
… Rats were divided into runners (had access to running wheel) and non-runners (their running wheels were immobilised). Two weeks after injection of the neurotoxin, the rats were injected with apomorphine and the number of ipsilateral and contralateral rotations was counted with contralateral …
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Neural substrates of avoidance behavior: The afferent limb
… the rabbit sitting in a large activity wheel was presented with two tones. One tone the positive conditional stimulus (CS+), predicted a mild foot-shock, the other tone (CS$-$) did not. The rabbit could learn to avoid the footshock by locomoting in the running wheel. Using a neuronal …
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The Effect of Exposure to Aversive Stimuli on Activity Based Anorexia
… during baseline and limited food access with running wheel access (ABA) phases influences weight loss in the ABA procedure. In the first experiment, twentyseven male Sprague-Dawley rats were divided into three conditions for extended periods across days: immobilization and light, elevated …
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Voluntary wheel running mitigates hyperglycemia-induced depressive-like behavior and increases hippocampal BDNF levels in male mice.
… mice in the exercise group had voluntary running wheel access in their home cage for 6 weeks. As anticipated, STZ induced depressive-like behavior. Exercise attenuated behavioral deficits in the forced swim and splash test. Tissue analyses found that exercise affected hippocampal …
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Effects of physical exercise and exercise-induced adult hippocampal neurogenesis on conditioned place preference for cocaine in mice
… neurogenesis. The main findings were that wheel running accelerated extinction of CPP when running occurred entirely after drug conditioning, whereas running delayed extinction when administered before conditioning, and that running approximately doubled adult hippocampal neurogenesis. …
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Non-Photic Phase Shifting: Acetylcholine and Arousal
… stimuli include confinement to a novel running wheel, and sleep deprivation by gentle handling. It was hypothesized that these stimuli both provide a sustained level of behavioral arousal to the animals in order to bring about phase shifts. If this was the case, then neurotransmitters …
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Délétion endothéliale de SHP-1 prévient la sénescence et rétablit l’angiogenèse des cellules endothéliales vasculaires en condition de diabète
… limb function (distance traveled in a running wheel) and formation of new collateral vessels in ischemic muscle were significantly reduced in DM mice compared to NDM mice. These effects of diabetes were prevented by the EC-specific deletion of SHP-1. In vitro, the use of a dominant …
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The Role of Notch1 in Adult Hippocampal Neurogenesis and Function
… neurospheres with extended passaging. While non-running Notch1 iKO mice had fewer YFP+ SGZ cells relative to wild type littermates, Notch1 iKO mice given 30 days access to a running wheel had equal number of YFP+ SGZ cells relative to controls, suggesting that running rescued total YFP+ SGZ cell …
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Neuroplastic Adaptations to Exercise Training and Detraining
… exercised spontaneously using a voluntary running wheel. Following the specified training regimen for each study, a multitude of ET indices were obtained, including: maximal oxygen consumption, percent body fat, resting heart rate and heart weight-to-body weight ratios. The brain was …
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The impact of physical activity on statin-associated skeletal muscle myopathy
… with (Acct)/without (Nov) the prior 2 weeks of wheel running (WR). Daily WR distance was recorded. At 4 weeks, plantarflexor isometric force and grip strength were measured. mtDNA, 4HNE, and atrogin-1 and PGC1-α were measured as markers of mitochondrial content by real time PCR, ELISA, real time …
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Effects of exercise and phytoestrogens on white adipose tissue health in estrogen deficient rodents
… underlying mechanisms to determine how voluntary wheel running (Chapter 3) or a diet rich in phytoestrogens (SOY) (Chapter 4) can improve WAT health following OVX in rodents. Female OVX rats selectively bred for high (HCR) or low (LCR) intrinsic aerobic capacity were fed a high fat diet (HFD; 45%) …
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Mass spectrometry-based identification and quantitation of endogenous peptides in complex biological matrices
… (CPP) for cocaine in mice that have access to a running wheel after CPP training. MS measurements have yielded both known and novel candidate peptides that show relative abundance changes with exercise and context re-exposure, which yields insight into the biochemical mechanisms driving the …
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Anorexia nervosa: investigation of markers of neuroinflammation, oxidative stress and synaptic plasticity using the activity-based anorexia rat model.
… feeding schedule with unlimited access to a running wheel to successfully reproduce the severe weight loss and hyperactivity typical of human AN. In addition, we measured protein expression of other regulators of oxidative stress in the dHPC (NOX2, NRF2, PRXSO3, SRNX1, HO-1) and mRNA levels …
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Low load endurance activity and green tea extract represent potential therapies for Duchenne muscular dystrophy
… and RunGTE mice were given free access to a running wheel for 3 weeks while SedNorm and SedGTE mice were restricted to normal cage movement. At the end of 3 weeks, mice in each treatment group were sacrificed and assessed for daily and weekly running distances, content of actin and myosin …
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Liposomal verkapselte Glukokortikosteroide in der Therapie der mdx-Maus als Modell der Duchenneschen Muskeldystrophie
Die Behandlung der DMD mit GS als einzige derzeit etablierte Langzeitbehandlung wird durch schwerwiegende Nebenwirkungen limitiert. Mittels liposomaler Verkapselung von GS kann durch hohe lokale Wirkspiegel bei geringen systemischen Konzentrationen ein günstigeres Wirkungs- Nebenwirkungs-Profil …
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