Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"rotaviruses"”.
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A comparison study of efficacy of food sanitizers with fresh leafy vegetables with different surface properties and analysis of the rotavirus replication cycle after inactivation by food sanitizers
… sanitizers Tsunami® 100 and malic acid + TDS on rotaviruses attached onto three cultivars’ surfaces with different surface properties. Moreover, we investigated the inhibitory effects of the sanitizers on the rotavirus replication cycle at a molecular level. As a result, while differences of …
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Porcine rotavirus adsorption to 24 salad vegetables and sanitization by free chlorine
… In this study, we determined the number of rotaviruses adsorbed on produce surfaces using group A porcine rotaviruses and 24 cultivars of leafy vegetables and tomato fruits. We also characterized the physicochemical properties of each produce’s outermost surface layer, known as the …
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Development of a New Class of Viral Disinfectants: Enzymatic Inactivation of Sa-11 Rotavirus
… dehydration and high mortality in the young. Rotaviruses are inactivated only by corrosive and toxic disinfectants. In this study, the effects of bacterial proteases as a new type of disinfectants on simian rotavirus (SA-11) were analyzed. SA-11 rotavirus replicates in cells causing cytopathic …
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Phase Separation Mediated Compartmentalisation of Rotavirus Replication
… replication and viral particle assembly in rotaviruses. Intrinsically disordered proteins are key drivers of LLPS. In rotaviruses, the disordered protein NSP5 binds the RNA chaperone NSP2, viral RNAs and other viral proteins to form replication factories known as viroplasms. Early in …
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The Role of Humoral Immunity in The Resolution of Rotavirus Infection in Mice
The immune response to rotaviruses has been studied extensively in several animal species. However, the importance of a humoral immune response in the resolution of active rotavirus infection has not been investigated directly. Most animals became resistant to rotavirus-induced diarrhea after a …
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Biochemical characterization of the nucleic acids of some human and animal viruses
… viruses. In Part II, the genomes of four rotaviruses were studied. "Simian agent 11" (SAll) and "offal agent" (OA) were cell culture-adapted strains, whereas "epizootic diarrhoea of infant mice virus" (EDIM) and "infantile gastroenteritis virus" (IGV) were isolated from stool specimens. …
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Investigating the dynamic nature of biomolecular condensates that support rotavirus replication
Group A rotaviruses (RVAs) induce the formation of viral replication factories, termed viroplasms, where new viral particle packaging and genome replication occur. The formation of such factories is driven by liquid-liquid phase separation (LLPS) of an intrinsically disordered phosphoprotein NSP5, …
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Secretion of the rotavirus VP7 capsid glycoprotein from polarised epithelial cells
… implementation of rotavirus vaccination, rotaviruses remain a major cause of severe diarrhoeal disease in infants and young children worldwide. Rotavirus is a double-stranded RNA (dsRNA) non-enveloped virus that infects polarised epithelial cells lining the upper region of the small …
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Identification and characterization of an enterocyte receptor for group A porcine rotavirus
Rotaviruses are the most common agents of viral diarrhea in the young of many species, including piglets. A virus-host cell binding assay was developed and used to investigate specific binding between Group A porcine rotavirus and MA-104 cells or porcine enterocytes. A variety of glycoconjugates …
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Determinants of Core Shell Dependent Rotavirus Polymerase Activity
Rotaviruses (RVs) are medically significant gastrointestinal pathogens and are a leading cause of childhood mortality in many countries. The RV RNA-dependent RNA polymerase, VP1, synthesizes RNA during viral replication only in the presence of another RV protein, VP2, which comprises the innermost …
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Resin-based method for concentration of enteric viruses and F-RNA coliphages from water samples
… Enteric viruses such as noroviruses, rotaviruses, adenoviruses and hepatitis viruses are dispersed by fecal contamination and are a major cause of waterborne diseases in the US and worldwide. Given the variety of viral enteric pathogens and their particular growth requirements, their …
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Antigenic Relationship of Different Porcine Rotavirus Isolates and the Identification of a New Porcine Strain
The problem. Currently, only one strain of porcine rotavlrus has been reported. This strain, designated OSU, has been attenuated and is currently available as a federally licensed, live oral vaccine for pigs. This study is concerned with the antigenic relationship of the OSU vaccine strain to four …
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Expression Of Cholera Toxin B Subunit-rotavirus Nsp4 Enterotoxin Fusion Protein In Transgenic Chloroplasts
… with approximately one million deaths annually. Rotaviruses belong to the family Reoviridae and are spherical 70-nm particles. The virus genome contains 11 segments of double-stranded RNA, each encoding a viral capsid or nonstructural protein. The identification of a rotavirus nonstructural …
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Determination of the prevalence and diversity of viral gastroenteritis infections and secretor status in the elderly population of the Tshwane region in South Africa
… with different degrees of infection by rotaviruses and noroviruses. A total of 1 012 stool specimens from elderly patients were collected over an 18-month surveillance period, of which 340 specimens met the inclusion criteria and were tested. Virus screening was performed using a …
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Exploring meaning-making among those who are identified by scientists as vaccine-resistant, vaccine-hesitant, or vaccine-sceptical
… These include vaccinations for the BCG, Polio, Rotaviruses, Pneumonia, and Diphtheria. They also receive vaccinations for tetanus, acellular pertussis, inactivated polio vaccine, and a combination of Haemophilus influenzae type B and hepatitis B and measles. Vaccinations and boosters continue …
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Mechanisms of Immunomodulation By Probiotics: Influence of Lactobacilli On Innate and T Cell Immune Responses Induced By Rotavirus Infection and Vaccines
My dissertation research focused on studying mechanisms of immunomodulation by probiotic lactobacilli on innate and T cell immune responses induced by rotavirus infection and vaccines in a gnotobiotic pig model of human rotavirus (HRV) infection and vaccination. We first studied the effects of …