Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"robo1"”.
-
Multiple roles for Robo1/2 repellent receptors in guiding the facial nucleus and nerve
… mutations in the chemorepulsive receptors Robo1 and Robo2, we found that these proteins are necessary for guiding the cell bodies and axons of the branchiomotor aspect of the facial nerve. In mutants, most axons do not make it to their motor exit point, and instead project into the …
-
The Role of Slit/Robo Signalling in Peripheral Nerve Regeneration
… infiltrating into the nerve bridge expressed Robo1 strongly. The Slit2, Slit3 and Robo1 single adult mutants show normal sciatic nerve morphology, but Slit3 and Robo1 single and double mutants had severely disrupted axon trajectories following sciatic nerve transection. However, Robo1 mutants …
-
Dissecting the Genetic Basis of Convergent Complex Traits Based on Molecular Homoplasy
… these include a group of 6 genes from the ROBO1 axon guidance pathway. In birds, I found ROBO1 and its ligand SLIT1 show convergent differential expression in the motor output song nucleus of the three independent lineages of vocal learners but not in analogous brain areas of vocal …
-
Genetic Modulation of the Neonatal Neural Processing of Speech at High and Low Familial Risk for Developmental Dyslexia
… loci were analysed (DCDC2, KIAA0319, ROBO1 and DYX1C1) based on the neonatal blood-spot samples. Electroencephalography (EEG) was used to assess the new-born infants’ channel-to-channel network coherence and their neuronal oscillatory processing of prosodically enhanced speech. We …
-
Role of Slit2 in Reducing Complications after Surgical Brain Injury
… investigated the role of Slit2 and its receptor Robo1 in reducing neuroinflammation after SBI. Lastly, the third aim investigated the role of Slit2 and its receptor Robo4 in stabilizing the BBB after SBI.</p> <p>Our findings showed that endogenous Slit2 increased in the perisurgical site in …
-
Genetic Analysis of Drosophila Stomatogastric Nervous System
… analysis of Dscam1, Dscam1 frazzled and Dscam1 robo1 double mutants, showing that the subtle phenotypes observed in Dscam1 mutants alone are not enhanced nor suppressed by frazzled and/or robo mutations. Moreover, I aimed to model Down syndrome gut nervous system defects in order to elucidate …