Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"rmTBI"”.
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The role of Substance P in chronic traumatic encephalopathy
… to repetitive mild traumatic brain injury (rmTBI). CTE has attracted significant attraction over the past few years due to the high incidence of sports-related head injuries and the emergence of dementia-like symptoms many years following active play. In addition, patients with suspected CTE …
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Antioxidant Biomarkers and Nutraceutical Therapeutics in Neurodegeneration and Neurotrauma
… athletes, are at high risk for repetitive mTBI (rmTBI). There are currently no FDA approved treatments for rmTBI for high-risk populations. We propose Immunocal®, a glutathione precursor supplement, as a preventative and restorative treatment for rmTBI. We show that Immunocal® significantly …
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Cognitive, Psychiatric, And Neuropathological Manifestations Of Repetitive Mild Traumatic Brain Injury
… Repetitive mild traumatic brain injury (rmTBI) has been linked to the development of chronic traumatic encephalopathy (CTE). The neurodegeneration accompanying CTE occurs over many years following repeated head impacts and is characterized by progressive brain atrophy, accumulation of …
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Experimental and Finite Element Evaluation of Mild Traumatic Brain Injury
… cumulative injury risks. To address repetitive rmTBI as observed in sports and military settings, a novel Whole Body Deceleration (WBD) model, based on rapid acceleration-deceleration, was introduced. This model induced rmTBI in rats, with motor function and anxiety-like behaviors assessed …
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The Effect of Traumatic Brain Injury On Tau Pathology By A Potential Seeding Mechanism
… with moderate-severe TBI or repetitive mild TBI (rmTBI) and examined tau pathology and spreading. Moreover, the earliest detected tau seeds induced following rmTBI were tested for seeding capability by <em>in vivo</em> bioassay. This proposal provides novel molecular mechanisms for these …
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The Role of Age and Model Severity on Cortical Vascular Response Following Traumatic Brain Injury
… We demonstrated that a repetitive mild TBI (rmTBI) can induce collateral remodeling in C57BL/6 but not CD1 mice; however, CCI injury had no effect on collateral changes in either strain. Together, these findings demonstrate an age-dependent and species/model dependent effect on vascular …
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The development of a novel composite score to characterize effect size of behavior and histopathology changes after a repetitive mild traumatic brain injury
In this paper, we investigate the potential for the development of a composite score investigating population-level phenotype changes in a mouse model of traumatic brain injury. Traumatic brain injuries (TBI) are a growing concern in the United States because the number of individuals impacted by …