Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"risk of recurrence"”.
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Molecular profiling in early stage IB1 squamous cell carcinomas of the uterine cervix.
Treatment of tumors of the cervix is based on clinical staging of disease. The International Federation of Gynaecology and Obstetrics system (FIGO staging) has established a system whereby cervical cancers are staged on the basis of anatomical extent of the tumor. Microinvasive tumors most often …
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Factors affecting recurrence of intrahepatic duct stone and factors affecting development of cholangiocarcinoma after initial treatment of intrahepatic duct stone
… biliary cirrhosis, and is an important risk factor for cholangiocarcinoma, which has a grave prognosis. Nevertheless, its intractable nature and high recurrence rate complicates treatment. Therefore, we investigated factors affecting recurrence of hepatolithiasis and factors affecting …
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Dissecting The Molecular Mechanism of Early Tumor Dissemination In Non-Small Cell Lung Cancer
<p>Lung cancer is the most common cause of cancer related death in the United States and worldwide. It has been shown that 30%-55% of patients with early stages of non-small cell lung cancer (NSCLC) developed and died of recurrence after curative resection, suggesting that tumor cell dissemination …
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The relationship between BRAF genetic alterations and the risk of tumour recurrence in Pilocytic Astrocytomas in children diagnosed at Red Cross Children's Hospital over a 33-year period
… rate between 75% to 100%. 2,3 Optimal treatment of partially resected, deep anatomic location and recurrent tumours are challenging. Over the past decades, PAs have been the object of an increasing number of molecular studies which tried to identify favourable and unfavourable prognostic factors. …
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Symptoms Experienced By Post-Menopausal Breast Cancer Survivors On Aromatase Inhibitors: A Secondary Analysis Of Baseline Data
… Aromatase Inhibitors (AI) is designed to reduce risk of recurrence and improve survival. AI therapy is associated with a variety of symptoms including musculoskeletal complaints, which have contributed to discontinuation of treatment. It is significantly important to explore the symptom profile …
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Blood Neutrophil-to-Lymphocyte Ratio predicts tumor recurrence in patients with hepatocellular carcinoma within Milan criteria after hepatectomy
… Ratio (NLR), has been reported as one of the adverse prognostic factors for HCC patient. The purpose of this study was to evaluate whether NLR could predict the risk of recurrence and death for the HCC patient confirming to Milan criteria after hepatectomy. Methods: Retrospective …
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Importância da atenção farmacêutica na adesão ao tratamento com anastrozolem um hospital oncológico de João Pessoa-PB
… world and the most common among women. The use of oral antineoplastic agents have been shown to decrease the risk of recurrence and mortality, and therefore, adherence to treatment is critical to achieve the expected results. This study aims to evaluate the importance of pharmaceutical care in …
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The impact of positive margins and crypt involvement in excisional procedures of the cervix on recurrence rates of premalignant diseases of the cervix
… margins and crypt involvement increased the rate of recurrence of premalignant disease in patients who had excisional procedures. METHODS In this retrospective review of the colposcopy database, patient records and pathology database, women who had cervical excisional procedures at the Groote …
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Breast Cancer Patient Preparedness for Transition to Survivorship: Individualized Survivorship Care Plans
… For breast cancer survivors, after-effects of surgery, radiation and chemotherapy can be substantial, and recurrence is a concern requiring constant surveillance. National healthcare organizations have promulgated guidelines that include providing individualized survivorship care plans …
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Treatments and outcomes in bipolar disorder
… episodes and patients have a markedly increased risk of suicide. Pharmacological and psychological treatments for bipolar disorder have proven efficacy in clinical trials yet the generalizability of current evidence to routine clinical practice is contested. This thesis presents studies on …
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Cyclin B1 Mediates The Effect of Uchl1 In Promoting Cell Cycle Progression In Uterine Papillary Serous Carcinoma
… serous carcinoma (UPSC) is an aggressive form of endometrial cancer with poor survival rates and a high risk of recurrence. The rarity of UPSC poses challenges to the discovery of novel targeted therapies. Therefore, the purpose of this dissertation was to identify novel therapeutic targets …
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Expression of X-linked Inhibitor of Apoptosis Protein in Neoplastic Thyroid Disorder
X-linked inhibitor of apoptosis protein (XIAP) is associated with tumor genesis, growth, progression and metastasis, and acts by blocking caspase-mediated apoptosis. In the present study, we sought to evaluate the expression patterns of XIAP in various neoplastic thyroid disorders and determine the …
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Choosing Mastectomy: A Qualitative Exploration of the Increasing Mastectomy Rates in Women with Early-stage Breast Cancer
Context: Rates of Unilateral (UM) and contralateral prophylactic mastectomy (CPM) for early-stage breast cancer (ESBC) have been increasing. Numerous factors for this rise have been suggested including the surgeon's preference, the patient's choice and the external environment. Objectives: A …
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Krūties carcinoma in situ tipai, diagnostika, gydymas ir prognozė /
SUMMARY Carcinoma in situ is a non-invasive form of breast cancer characterised by abnormal cell growth in the ducts or lobules of breast tissue. Breast carcinoma in situ consists of two subtypes: ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS). Breast carcinoma in situ is most …
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Deep Learning and Radiomics Based Outcome Prediction for Cancer Patients
The accurate prediction of cancer patient treatment outcomes is essential for personalized treatment planning and improved treatment outcome. The use of machine learning methods, such as deep learning (DL) and radiomics, has been gaining attention in the field of cancer research for predicting …
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Outcomes of renal transplantation in patients with lupus nephritis: a single centre study in Cape Town
… (lupus nephritis [LN]) constitutes a feature of systemic lupus erythematosus (SLE) in up to 50 - 70% of patients with the disease. Although most LN patients are suitable for renal transplantation when they develop end stage renal disease (ESRD), the risk of recurrence of LN …
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The Risk of Seizure Recurrence Following a First Unprovoked Seizure in Childhood: An Extended Follow-Up
… seizure has been a controversial issue. Results of long-term outcome after a first unprovoked seizure in children are extremely variable. Untoward effects of long-term AEDs(antiepileptic drugs), especially cognitive dysfunction and behavioral problems, are important especially in developing …
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The Healing Power of a Whole Foods, Plant-based Diet: A Nutrition Prescription for Cancer
… is quickly overtaking infectious diseases as one of the biggest threats to population health worldwide (Egger, 2012). Studies have shown that plant based diets are effective at reducing prevalence but are also a viable complimentary treatment approach to healing. Further investigation is needed …
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Feasibility and Acceptability of Time-Restricted Eating During Chemotherapy for Breast Cancer
… come with side effects that decrease quality of life and may lead to factors that increase the risk of recurrence, cardiovascular disease and all-cause mortality. Additionally, social determinants of health may further increase these risks. This dissertation research examines community-level …
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A Randomized Controlled Trial for Treatment of High-Grade Cervical Lesions Among HIV-Infected Women in Kenya
… consistently been reported to have higher burden of human papillomavirus (HPV) infection, persistent HPV infection, and cervical pre-cancerous lesions than HIV-uninfected women. These lesions, if left untreated, can progress to cervical cancer. For women with high grade cervical pre-cancer, …
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