Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"risk of fracture"”.
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Chemo-poro-elastic fracture mechanics of wellbore cement liners : the role of eigenstress and pore pressure on the risk of fracture
… wells have been drilled at a mean annual rate of 24,500. Moreover, an investigation in the Marcellus region revealed a 3.4% incidence rate of well-barrier leakages that were caused primarily by casing and cementing problems. Considering the detrimental consequences even a single failed well can …
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An estimation of risk of Colles’ fracture using model-based interpretation of bone profiles
In this thesis a technique to estimate the risk of Colles’ fracture using ordinary radiographs, instead of performing expensive DXA scans is described. The risk of fracture was estimated by maximum stress of the bone which was modelled as a parallel sided tube. Grey-level profiles across the radius …
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Evaluation of Neuromuscular Electrical Stimulation as a Bone Loss Countermeasure on a Long Duration Mars Mission
… bone loss, in part, due to the absence of the skeletal loading normally experienced on Earth. The current ISS exercise regimen is not expected to sufficiently reduce the risk of fracture on a long duration mission to Mars (>6 months) and additional exercise cannot be added as exercise is …
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Bone fracture toughness of estrogen deficient rabbits
Bone mass is commonly used as an indicator of fracture risk. It has been shown in numerous studies that bone loss causes increased bone fragility and risk of fracture. It has also been shown that 50% of patients with osteoporotic vertebral compression fractures have the same bone mass as normal age …
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Risk assessment for osteoporotic fractures among men and women from a prospective population study: the EPIC-Norfolk study
Osteoporotic fractures are a major and increasing clinical and public health concern internationally. Identification of individuals at high risk for fragility fractures may enable us to target preventive interventions more effectively. In this thesis, I aimed to evaluate novel risk factors for …
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Biomechanics of North Atlantic right whale bone : mandibular fracture as a fatal endpoint for blunt vessel-whale collision modeling
… Atlantic right whale, Eubalaena glacialis, one of the most critically endangered whales in the world, is subject to high anthropogenic mortality. Vessel-whale collisions and entanglement in fishing gear were indicated in 27 (67.5%) of the 40 right whales necropsied between 1970 and December …
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Interactions Between Aging and Chronic Kidney Disease on the Skeleton
In the US, 15% of adults have chronic kidney disease (CKD). While CKD occurs across all ages, the prevalence is highest in the aged, with ~40% of individuals over age 65 having some form of CKD. CKD and aging are each independently associated with higher fracture risk, and thus overlaying CKD in …
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Nonlinear models with measurement error: Application to vitamin D
… to maintain healthy bones and to reduce risk of fracture. It is difficult, however, to determine recommended intake levels due to the complexity of the metabolism of the vitamin D we consume. Vitamin D status depends on factors other than consumption of vitamin D from food and …
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Algebraic level sets for CAD/CAE integration and moving boundary problems
<p>Boundary representation (B-rep) of CAD models obtained from solid modeling kernels are commonly used in design, and analysis applications outside the CAD systems. Boolean operations between interacting B-rep CAD models as well as analysis of such multi-body systems are fundamental operations on …
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Characterizing Femoral Structure of the Ts66Yah Mouse Model of Down Syndrome
… is caused by the partial or complete trisomy of human chromosome 21 (Hsa21) and can result in skeletal deficits, including lower bone mineral density (BMD) and increased risk of fracture and osteoporosis or osteopenia earlier than the general population. Mouse models of DS have been developed …
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Photodynamically Activated Multifunctional Chitosan Nanoparticles to Disinfect and Improve Structural Stability of Dentin
… root canal treatment failure. Thus the success of endodontic treatment depends on the complete elimination of bacteria and prevention of bacterial recolonization in the root canal system. The major challenge for conventional root canal disinfection strategies is the ability of bacteria to …
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A Biomechanical Analysis of One-Third Tubular Plates for the Treatment of Benign Lesions in the Distal Femur
The purpose of this study was to evaluate the use of one-third tubular plates for the treatment of benign defects in the medial distal metaphysis of the femur. Benign cysts are a common occurrence in long bones, and are of concern in load-bearing bones, such as the tibia and femur. These …
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Multi-objective design optimization of a mobile-bearing total disc arthroplasty considering spinal kinematics, facet joint loads, and metal-on-polyethylene contact mechanics
… therapies fail. Unfortunately, a high incidence of revision surgery exists due to postoperative complications including abnormal kinematics, facet joint arthritis, and implant failures. However, TDA is still an attractive option, since an optimally designed artificial disc is expected to …
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The impact of food and nutrient intake on bone from childhood to early adulthood
Development of peak bone mass during childhood to early adulthood has been considered as a major determinate of risk of fracture and osteoporosis later in life. The purpose of this project was to determine the impact of food and nutrient intake on bone from childhood to early adulthood using mixed …
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A shape analysis approach to prediction of bone stiffness using FEXI
The preferred method of assessing the risk of an osteoporosis related fracture is currently a measure of bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA). However, other factors contribute to the overall risk of fracture, including anatomical geometry and the spatial …
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The muscle-bone in children and adolescents with and without cystic fibrosis
… with cystic fibrosis(CF) have an increased risk of developing osteoporosis and fragility fractures in young adulthood, which may be caused by poor growth. The aim was to investigate whether sex and disease status modified the relationship between: 1) puberty and bone, and 2) muscle and bone. …
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Physical activity and its effect on bone in the short- and long- term perspective.
… a growing problem worldwide where Sweden has one of the highest fragility fracture incidences in the world. The growing years are thought to be an opportune time to build strong bones and the enhancement of peak bone mass (PBM) has been suggested as a prevention strategy for osteoporosis. Most …
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ASSOCIATION BETWEEN CONCOMITANT USE OF BISPHOSPHONATES AND SEROTONIN REUPTAKE INHIBITORS AND INCREASED RISK OF OSTEOPOROTIC-RELATED FRACTURES: AMONG COMMUNITY-DWELLING POSTMENOPAUSAL WOMEN
… to treat these conditions. Inhibitory effects of BPs on osteoclasts are responsible for the reduction in fracture risk. SSRIs, however, are associated with increased fracture risk through decreasing osteoblasts and increasing osteoclastic activity. These effects of SSRIs could attenuate the …
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The Impact of Vitamin D Status upon Markers of Athlete Health
Introduction At present there is a pandemic of low serum vitamin D (25[OH]D) concentration, partly due to a lack of sun exposure (the primary route for synthesis) and modern lifestyle choices. The bioactive form of vitamin D, 1,25-dihydroxyvitamin D (1,25[OH]2D3) exerts its biological activity by …