Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"rifabutin"”.
-
Effektivität der neuen 7-Tage-Tripel-Therapie mit Esomeprazol, Rifabutin und Amoxicillin bei Infektionen mit Makrolid- und Imidazolresistenten Helicobacter pylori Stämmen
… doppeltresistentem Helicobacter pylori, mit der Rifabutin-Tripel-Terapie ( ERA – 2 x 20 mg Esomeprazol, 2 x 150 mg Rifabutin und 2 x 1000 mg Amoxicillin über 7 Tage) oder der modifizierten Hochdosis-Dualtherapie (mOA – Omeprazol 3 x 40 mg und 3 x 1000 mg Amoxicillin über 14 Tage) behandelt. Die …
-
Pharmacometrics to characterize pharmacokinetics and optimize treatment in understudied populations
… with cardiopulmonary bypass; optimizing dose of rifabutin, an antibiotic used for TB, during lopinavir/ritonavir (LPV/r)-co treatment in children with TB-HIV co-infection; showcasing a model-based adherence monitoring tool using enalapril, an angiotensin-converting enzyme inhibitor for …
-
Effect of Drugs on Rabbit Retina
… ocular examination and histochemical methods. Rifabutin is a broad spectrum antibiotic with known ocular adverse effects (corneal opacities, uveitis and vascular retinopathy) in the human eye. In the rabbit eye rifabutin causes lens discoloration and it significantly reduces both total rod-cone …
-
Pharmacometrics of dolutegravir and tenofovir: a quantitative approach to characterise drug-drug interactions, pharmacogenetics and optimise treatment
… with the antituberculosis drugs rifampicin and rifabutin and with the antimalarial drugs artemether-lumefantrine and artesunate-amodiaquine. We also describe the pharmacokinetics of tenofovir when dosed as either tenofovir disoproxil fumarate or tenofovir alafenamide in South Africans living …
-
Identifying cross-species regimens for the treatment of rapid-growing and slow-growing nontuberculous Mycobacterium pulmonary infections
… infection. Macrolides, fluoroquinolones, and rifabutin demonstrated comparable in vitro potency, but had variable performance across models. Azithromycin and ofloxacin were also effective and displayed synergy when combined with bedaquiline. Combinations of bedaquiline with azithromycin or …
-
Macrolide Resistance in Mycobacterium avium
… unrelated agents, including ciprofloxacin, rifabutin, and ethidium bromide. Addition of carbonyl cyanide m-chlorophenylhydrazone (CCCP) did not lower minimal inhibitory concentrations (MICs) for ciprofloxacin or ethidium bromide. Cell-free extracts of the strains were as sensitive to …
-
Evaluation of Intestinal Microbial Diversity and a New Antibiotic Regimen in Crohn's Disease Patients
… Three antibiotic drugs – Clarithromycin (CLA), Rifabutin (RIF), and Clofazimine (CLO) have been used to treat CD patients suspected with MAP infection. However, the outcome has been controversial. The treatment dosage is high, the duration is long, and the reported drug side effects resulted in …
-
Evaluation of the costs of managing cutaneous adverse drug reactions to first-line TB therapy in South African TB patients
… second-line regimens containing rifabutin, bedaquiline and delamanid cost 44-55% less than drug rechallenge depending on the drug regimen used ($2,651/patient to $3,276/patient). Sensitivity analyses indicated that drug rechallenge was most sensitive to hospitalisation costs, …