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Showing 1 to 3 of 3 for “"ricin B-chain"”.
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Ricin B Chain-Insulin Fusion Protein Immunomodulation of Type 1 Diabetes
… proinsulin was linked to the non-toxic B chain of ricin—an enterocyte-binding plant lectin that possesses intrinsic cell-delivery and immunostimulatory properties. The human proinsulin (INS) ricin toxin B chain (RTB) fusion protein was expressed in <em>Escherichia coli </em>and purified …
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Receptor mediated targeting of liposomes
… using either α-melanocyte stimulating hormone or Ricin-B-chain as ligands for promoting the binding of liposomes to cells. α-melanocyte stimulating hormone has been conjugated to liposomes and to Ricin-A-chain via the Lys₁₁ residue without significant loss of biological activity. The resulting …
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Engineering of the RTB Lectin as a Carrier Platform for Proteins and Antigens
… galactose/N-acetyl-galactosamine specific lectin ricin B-chain (RTB) is especially attractive in possibly fulfilling a carrier role due to its well-characterized endocytotic trafficking and its efficacy over a wide range of cell types. By producing RTB recombinantly in plants it is possible to …