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Showing 1 to 3 of 3 for “"ribotoxins"”.

  1. Biochemical and Structural Studies of RNA Modification and Repair

    … not only repairs tRNAAsp and tRNAArg cleaved by ribotoxins colicin E5 and colicin D, respectively, but also adds a methyl group to the same 2'OH group, which acts as a nucleophile during RNA cleavage by the ribotoxins. As a result, the repaired tRNAs resist the re-attack by ribotoxins. This …

    uiuc Repository record for Biochemical and Structural Studies of RNA Modification and Repair (opens in a new tab)

  2. Biochemical and structural studies of RNA damage and repair in bacteria

    … own survival and growth. Many organisms utilize ribotoxins to respond to cellular stress or to kill competing organisms. Ribotoxins are site-specific endonucleases which typically target RNA molecules that are necessary for translation mainly, tRNAs and rRNAs which can result in their loss of …

    uiuc Repository record for Biochemical and structural studies of RNA damage and repair in bacteria (opens in a new tab)

  3. Biochemical and Structures Studies of tRNA Modificaton and Repair Enzymes

    … Pnkp/Hen1 could not be cleaved again by the ribotoxins. Thus, unlike eukaryotic Hen1 involved in RNAi, bacterial Hen1 is part of a RNA repair and modification system.

    uiuc Repository record for Biochemical and Structures Studies of tRNA Modificaton and Repair Enzymes (opens in a new tab)