Global ETD Search
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Showing 1 to 2 of 2 for “"ribosome engineering"”.
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A General Platform for Ribosome Engineering
… approach. However, the properties of the natural ribosome limit existing work to close analogues of the canonical amino acids. This thesis develops a directed evolution technology to engineer ribosomes in vitro. The focus of this work is to create a general platform capable of identifying ribosome …
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Investigation of the Discoipyrroles and Other Marine Bacteria Derived Natural Products
… pathways using the methodology known as ribosome engineering will be discussed. This work demonstrates how the discovery and development of bioactive natural products can be enhanced by biosynthetic interrogations.