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Multi-color visualization and quantification of single RNA translation and HIV-1 programmed ribosomal frameshifting in living cells

Lyon, Kenneth Ray, Jr., author, Stasevich, Timothy, advisor, Munsky, Brian, committee member, Cohen, Bob, committee member, DeLuca, Jake, committee memberColorado State University. Libraries2019

… imaging modality was used to investigate ribosomal frameshifting during translation. Frameshifts occur through a ribosomal +1(-2) or -1 (+2) nucleotide(s) "slip" into another frame and are implicated in both human disease and viral infections. While previous work has uncovered many …

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