Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ribonucleoprotein granules"”.
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Multilayered regulation of translation: roles of rRNA modifications, alternative initiation factors, and RNA-binding proteins
… and participates in mRNA sequestration into ribonucleoprotein granules, influencing cellular responses to environmental stress. Together, these studies provide how translation initiation and elongation are fine-tuned through diverse molecular mechanisms, advancing our understanding of …
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Programmable Assembly of Elastin-like Polypeptides Within Droplet Microenvironments
… Lastly, we developed model functional ribonucleoprotein organelles composed of RNA-binding elastin-like polypeptides designed de novo, and show that these organelles temporally regulate gene expression within droplet-based protocells. Taken together, this body of work offers new …
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The role of the RNA-binding protein FUS in axonal organisation and disease
The role of the RNA-binding protein FUS in axonal organisation and disease In this thesis, I discuss the role of the RNA-binding protein Fused in sarcoma (FUS) in axonal organisation and disease. FUS aggregates in forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), and …