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Showing 1 to 12 of 12 for “"ribonucleases"”.
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An Investigation of Bacterial Ribonucleases as an Antibiotic Target
… 50S ribosomal subunits is processed by bacterial ribonucleases (RNases). RNases are also involved in the degradation and turnover of this RNA during times of stress, such as the presence of an antibiotic. This makes ribonucleases a potential target for novel antibiotics.</p><p>It was shown that …
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ΜΕΛΕΤΗ ΤΩΝ ΡΙΒΟΝΟΥΚΛΕΑΣΩΝ ΤΟΥ ΟΡΟΥ ΤΟΥ ΑΙΜΑΤΟΣ ΣΕ ΥΓΙΕΙΣ ΚΑΙ ΑΣΘΕΝΕΙΣ ΜΕ ΚΑΡΚΙΝΟ ΚΑΙ ΜΙΑΣ ΠΡΩΤΕΙΝΗΣ ΠΟΥ ΠΑΡΕΜΒΑΙΝΕΙ ΣΤΗ ΔΡΑΣΗ ΤΟΥΣ
FIVE RIBONUCLEASES WERE PURIFIED FROM THE SERUM OF NORMAL HUMAN SUBJECTS. THE PROPERTIES OF FOUR OF THEM WERE IDENTICAL TO THOSE OF THE SECRETORY TYPE RIBONUCLEASES (OPTIMUM PH 8 AND FASTER HYDROLYSIS OF POLY-C COMPARED TO POLY-K). THE FIFTH ENZYME, WITH THE LOWER MOL. SIZE, HYDROLYZED FASTER …
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Degradation of 23S rRNA in Azithromycin-Treated Ribonuclease Mutants of <em>Escherichia coli</em>.
… particle. When exposed to azithromycin, several ribonucleases in wild-type <em>Escherichia coli</em> cells degrade antibiotic-bound 50S precursor particles. Presumably, cells expressing one or more mutated ribonucleases will degrade the antibiotic-bound precursor less efficiently, resulting in …
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ΦΩΣΦΟΔΙΕΣΤΕΡΟΛΥΤΙΚΗ ΔΡΑΣΗ ΣΕ ΚΥΤΤΑΡΟΠΛΑΣΜΑ ΣΥΚΩΤΙΟΥ ΠΟΝΤΙΚΟΥ C3HB. ΚΑΘΑΡΙΣΜΟΣ ΚΑΙ ΜΕΛΕΤΗ ΙΔΙΟΤΗΤΩΝ ΤΕΣΣΑΡΩΝ ΕΝΖΥΜΩΝ
… ACTIVITY OF MOUSE LIVER CYTOPLASM IS DUE TO 2 RIBONUCLEASES. THEY ARE LOW MOLECULAR WEIGHT ENZYMES THAT RESIST ACID CONDITIONS BUT ARE DESTROYED AT 100 K FOR 10 MIN . THE ENZYMES SHOW DIFFERENT PRETENCES TOWARDS END-LABELLED NATURAL SUBSTRATES (55 RNA). RNASE I SHOWS THE SAME SPECIFICITY ASTHE …
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Synchrony of harmony and chaos in a dynamic, bacterial riboregulatory machine
… to as “RNA degradosomes”, are composed of ribonucleases, helicases, and other proteins of RNA metabolism. This dissertation focuses on the RNA degradosome of the representative Gram-negative bacterium, Escherichia coli, where the main component of the assembly is RNase E, a homotetrameric …
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Features of the Initiation of Translation of Two Plant Viral Messenger-Rnas
… specific regions of the RNA from attack by ribonucleases. Wheat germ 80S ribosomes protect a "limit" region 19-52 nucleotides from the 5'-terminus. Wheat germ 40S ribosomes protect a "limit" region 10-47 nucleotides from the 5'-terminus. Characterization of the ribosome protected regions …
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Fantastic ribonucleoprotein complexes and how to study them. Architectural principles of regulatory assemblies in bacteria.
… transcript is controlled by three key players: ribonucleases, RNA binding proteins (RBPs) and small regulatory RNAs (sRNAs). Together these form an information-rich regulatory network that exercises post-transcriptional control of gene expression. A key RBP in bacteria is Hfq, which is best …
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Endoribonukleazių poveikio ankstyviesiems bakteriofago T4 transkriptams tyrimas /
Phage T4 has developed a complex mechanism of ribonucleases control, which needs yet to be investigated. Apart from the impact of endoribonuclease RegB, no other effects of Escherichia coli- or phage-encoded proteins are known to be involved in the degradation of early mRNAs. This study has aimed …
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Biological Functions of ribonuclease 1 and angiogenin
Pancreatic-type ribonucleases (ptRNases) are a large family of vertebrate-specific secretory endoribonucleases. They catalyze degradation of many RNA substrates, mediating a variety of biological functions. The homology shared by ptRNases has enabled extensive biochemical characterization and …
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Interaction of Cu(II) ion with ribonuclease A in the native and unfolded states
<p>The binding of Cu(II) ion to ribonuclease A at various sodium perchlorate concentrations was studied as a function of Cu(II) ion concentration and pH using a Cu(II) ion electrode. Spectrophotometric studies of the same systems were also carried out. The copper binding studies were carried out at …
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Η ΡΙΒΟΝΟΥΚΛΕΟΛΥΤΙΚΗ ΔΡΑΣΗ ΤΟΥ ΚΥΤΤΑΡΟΠΛΑΣΜΑΤΟΣ ΤΟΥ ΠΡΩΤΟΖΩΟΥ TETRAHYMENA PYRIFORMIS
ΑΠΟ ΤΟ ΚΥΤΤΑΡΟΠΛΑΣΜΑ ΤΟΥ ΠΡΩΤΟΖΩΟΥ TETRAHYMENA PYRIFORMIS ΑΠΟΜΟΝΩΘΗΚΑΝ ΔΥΟ ΟΞΙΝΕΣ (Α, Β) ΚΑΙ ΜΙΑ ΟΥΔΕΤΕΡΗ (Γ) ΡΙΒΟΝΟΥΚΛΕΑΣΕΣ. ΜΕΛΕΤΗΘΗΚΕ Η ΕΠΙΔΡΑΣΗ ΤΟΥ ΡΗ, ΤΩΝ ΜΟΝΟΣΘΕΝΩΝ ΙΟΝΤΩΝ, ΤΩΝ ΔΙΣΘΕΝΩΝ ΚΑΤΙΟΝΤΩΝ, ΤΟΥ EDTA ΚΑΙ ΤΗΣ ΟΥΡΙΑΣ ΣΤΗ ΔΡΑΣΗ ΤΩΝ ΕΝΖΥΜΩΝ. ΜΕΛΕΤΗΘΗΚΕ ΑΚΟΜΑ Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΟΞΙΝΣΗΣ ΚΑΙ ΤΟΥ …
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ΚΑΘΑΡΙΣΜΟΣ ΚΑΙ ΙΔΙΟΤΗΤΕΣ ΤΡΙΩΝ ΚΥΤΤΑΡΟΠΛΑΣΜΑΤΙΚΩΝ ΡΙΒΟΝΟΥΚΛΕΑΣΩΝ ΑΠΟ ΣΥΚΩΤΙ ΠΟΝΤΙΚΟΥ
AN ACIDIC, A NEUTRAL AND AN ALKALINE RIBONUCLEASE WERE ISOLATED FROM MOUSE LIVER CYTOPLASM, BY GEL FILTRATION, ION EXCHANGE AND AFFINITY CHROMATOGRAPHY. THE ACIDIC RIBONUCLEASE HYDROLYSES RNA OPTIMALLY AT PH 6.2, IN THE ABSENCE OF SALTS AND AT PH 5.5 IN SOLUTIONS WITH 150 MM OF MONOVALENT SALTS. IT …