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Showing 1 to 2 of 2 for “"rhoA GTP-Binding Protein"”.
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Activated RhoA Positively Regulates Exchange Activity of PDZ-RhoGEF
RhoA plays a key role in regulation of the actin cytoskeleton, cell migration and cell shape. Rho GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This cycle is mediated by guanine nucleotide exchange factors (GEFs) that increase the rate of dissociation of GDP by …
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Regulation of p190RhoGEF by Activated Rho and Rac GTPases: Amplification and Crosstalk
The Rho family of monomeric GTPases regulates a wide range of cellular processes including cytoskeletal structure, motility, cell division, gene transcription, vesicular transport, and various enzymatic activities. Activation of Rho proteins largely depends on Rho Guanine nucleotide Exchange …