Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"reversible inactivation"”.
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Solutions to various problems in reversible cooling fMRI studies
… and look at the functional consequences of this (reversible) inactivation upon regions anatomically connected to the inactivated site. A number of issues need to be resolved before the reversible cooling technique can be used in fMRI studies. The solutions to a number of problems directly related …
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Drosophila CPEB, Orb2, a Putative Biochemical Engram of Long-term Memory
… Here, using tools that allow rapid and reversible inactivation of Orb2 protein I find that Orb2 activity is required for encoding and recall of memory. Blocking the Orb2 oligomerization process by interfering with the protein phosphorylation pathway or expressing an anti-amyloidogenic …
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Decision-making in the primate brain : formation, location, and causal manipulation
… between LIP responses and decisions, reversible inactivation of neurons in LIP had no measurable impact on decision-making performance. More generally, I show that decision-related activity does not necessarily play a causal role in choices. In the final experiment, I test whether the …
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Dependence of Visuomotor Behavior on Individual Layers of the Cat Lateral Geniculate Nucleus in the Normal Brain and Following Recovery From Destruction of Individual Layers
… structure generating saccades. During layer-A reversible inactivations, saccade success rate fell from 82.4% to 26.8%. Inactivations lowered amplitude and peak velocity, and increased saccade latency. In contrast, inactivating C layers had no affect on performance. All saccades from layer A and …
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Modelling the Neuropsychopharmacology of Obsessive-Compulsive Disorder in the Common Marmoset (Callithrix jacchus)
… discrimination retention. By contrast, similar reversible inactivation of the caudate nucleus produced marked deficits in visual discrimination performance (retention). In Chapter Five, the neural basis of action–outcome contingency knowledge was investigated by inactivating distinct regions of …