Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"reverse electron transport"”.
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Productivity, metabolism and physiology of free-living chemoautotrophic Epsilonproteobacteria
… (25 MPa, 24°C) with various combinations of electron donors/acceptors (H2, O2 and NO3 and 13HCO3) as a tracer to track carbon fixation. During short (18-24 h) incubations of low-temperature vent fluids from Crab Spa (9°N East Pacific Rise), the concentration of electron donors/acceptors and …
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Productivity, metabolism and physiology of free-living Chemoautotrophic Epsilonproteobacteria
… (25 MPa, 24°C) with various combinations of electron donors/acceptors (H₂ , O₂ and NO₃- and ¹³HCO₃-) as a tracer to track carbon fixation. During short (18-24 h) incubations of low-temperature vent fluids from Crab Spa (9°N East Pacific Rise), the concentration of electron donors/acceptors …
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Novel approaches to treat mitochondrial complex-I mediated defects in disease
… within complex I (CI) of the mitochondrial electron transport system has been implicated in a number of disease states ranging from cardiovascular diseases to neuro-ophthalmic indications. Herein, we provide three novel approaches to model and study the impacts of injury on the function of …
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Elucidating the mechanism of mitochondrial superoxide production in pro-inflammatory macrophages
… produce mitochondria derived superoxide by reverse electron transport (RET) at complex I. However, this has not been demonstrated and the mechanism of mitochondrial superoxide production is unknown. Furthermore, the influence of LPS induced metabolic reprogramming on mitochondrial ROS …
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Developing an adjunct therapy to mechanical thrombectomy in a murine model of stroke ischaemia reperfusion injury
… by succinate dehydrogenase (SDH). This drives reverse electron transport (RET) via complex I of the mitochondria to generate harmful reactive oxygen species (ROS) in a process known as RET-ROS. The SDH inhibitor disodium malonate (DSM) has been reported to enter cells via monocarboxylate …
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Developing methods for measuring mitochondrial redox status and membrane potential in the isolated perfused heart
… by dictating the thermodynamic likelihood of reverse electron transport (RET) at complex I and the production of reactive oxygen species (ROS) and may also influence Ca<sup>2+</sup> transport and the opening of the mitochondrial permeability transition pore (MPTP). However, it is not entirely …