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Showing 1 to 1 of 1 for “"retrorsine"”.
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Cell senescence and aging in carcinogenesis and liver repopulation
… laboratory and is based on the administration of retrorsine (RS), a naturally occurring alkaloid, as a preconditioning treatment. Rat liver exposed to RS and then transplanted with isolated normal hepatocytes is entirely replaced by donor-derived cells within a few months. Importantly, …