Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 154 for “"retinopathy"”.
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Inflammatory mediators in diabetic retinopathy
Diabetic retinopathy (DR) is the most feared complication of diabetes with an overall prevalence of 21.9-36.8% and may, if untreated, lead to severe visual disability or blindness. DR is histologically characterized by pericyte and endothelial cell loss, formation of acellular vessel strands, …
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Vessel identification in diabetic retinopathy
Diabetic retinopathy is the single largest cause of sight loss and blindness in 18 to 65 year olds. Screening programs for the estimated one to six per- cent of the diabetic population have been demonstrated to be cost and sight saving, howeverthere are insufficient screening resources. Automatic …
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Corpus callosum morphology in retinopathy-positive and retinopathy-negative Malawian children diagnosed with cerebral malaria
… investigated corpus callosum (CC) morphology in retinopathy-positive and retinopathy-negative pediatric survivors of cerebral malaria (CM). Participants were 20 children who were admitted to the Queen Elizabeth Central Hospital in Blantyre, Malawi, and satisfied the clinical case definition of …
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Premature vascular senescence during diabetic retinopathy
… a role for cellular senescence in diabetic retinopathy is unclear. Therefore, the aim of this study is to investigate the senescence profile of human retinal microvascular endothelial cells (HRMECs), to elucidate how this is affected by the diabetic milieu. <br/><br/>HRMECs undergo …
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Current therapeutic approaches for retinopathy of prematurity
… βάρους, όπως το μοντέλο Weight, IGF-1, Neonatal, Retinopathy of Prematurity (WINROP), είναι κρίσιμη για την έγκαιρη θεραπεία. Η φωτοπηξία με λέιζερ, που ιστορικά αποτελούσε το πρότυπο θεραπείας, προσφέρει παρατεταμένη υποστροφή της νεοαγγείωσης, ιδιαίτερα σε νόσο ζώνης II, αν και σχετίζεται με …
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Malarial retinopathy and neurovascular injury in paediatric cerebral malaria
… overlapping groups of subjects, all of whom had retinopathy positive cerebral malaria: children with admission ophthalmoscopy (n=817), children with admission fluorescein angiography (n=260), and children with admission angiography and MRI of the brain (n=134). Several retinal features are …
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Role of the sphingomyelin/ceramide pathway in diabetic retinopathy
Thesis (Ph. D.)--Michigan State University. Department of Microbiology and Molecular Genetics, 2010
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The role of VIP family members in diabetic retinopathy
Diabetic retinopathy (DR) is a microvascular complication of diabetes leading to blindness. Hyperglycemic/hypoxic microenvironment concurs to mechanical breakdown of blood-retinal barrier (BRB) as well as the aberrant angiogenesis activating many downstream target genes including inflammatory …
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Detection and Classification of Diabetic Retinopathy Pathologies in Fundus Images
Diabetic Retinopathy (DR) is a disease that affects up to 80% of diabetics around the world. It is the second greatest cause of blindness in the Western world, and one of the leading causes of blindness in the U.S. Many studies have demonstrated that early treatment can reduce the number of …
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Exploring the Role of the Inflammasome Pathway in Diabetic Retinopathy
Background: Diabetic retinopathy (DR) is the leading cause of vision loss among working-age adults worldwide, yet current treatments are inadequate to halt its progression. Studies suggest that dysregulated nucleotide-binding oligomerization domain (NOD)-like receptor protein 3 (NLRP3) inflammasome …
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Vascular breakdown in diabetic retinopathy: Role of connexin43 and possible interventions
Background: Diabetic retinopathy (DR) is a chronic vascular disease of the retina that can lead to vision loss. Current DR therapies, including anti-vascular endothelial growth factors, mainly target late-stage vascular defects and long-term treatments have been shown to contribute to geographic …
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Awareness of diabetic retinopathy among diabetics in the Cape Town Metropole
… To investigate the awareness of diabetic retinopathy (DR) among diabetics in the Cape Town Metropole by assessing: - Whether diabetics know that diabetes can affect their eyes. - Whether the awareness of DR differs according to subtype of diabetes, place of treatment (private versus public …
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A Deep Learning Based Pipeline for Image Grading of Diabetic Retinopathy
Diabetic Retinopathy (DR) is one of the principal sources of blindness due to diabetes mellitus. It can be identified by lesions of the retina, namely microaneurysms, hemorrhages, and exudates. DR can be effectively prevented or delayed if discovered early enough and well-managed. Prior studies on …
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Investigation of prolactin-related vasoinhibin in sera from patients with diabetic retinopathy
Wissenschaftlicher Hintergrund: In-vitro-Experimente und in-vivo-Studien mit Nagetieren zeigten, dass die N-terminalen 14,15, 16, 17 und 18 kDa-Fragmente (prolactin-related vasoinhibin, PRL-V) des menschlichen Prolaktins natürliche Inhibitoren der Neovaskularisation in der Retina sind. Diese …
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Optical Coherence Tomography Angiography and wide-field fluorescein angiography in Diabetic Retinopathy
Obiettivo: studiare i cambiamenti nella perfusione maculare nei pazienti affetti da edema maculare diabetico e valutare la fattibilità della fluorangiografia con ad ampio campo nella pratica clinica. Materiali e metodi: in questo studio di coorte retrospettivo sono stati inclusi pazienti caucasici …
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Benefits and accessibility of OCTA imaging for diabetic retinopathy and macular edema
Diabetic retinopathy (DR) and diabetic macular edema (DME) are among the leading causes of vision loss worldwide. Early detection and timely intervention are crucial in decreasing the risk of vision impairment worldwide. Optical Coherence Tomography Angiography (OCTA) is an emerging imaging …
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Assessment of factors associated with diabetic retinopathy among diabetic patients in Zambia
… of diabetes mellitus in Africa. Diabetic retinopathy is a common complication of diabetes mellitus that causes visual impairment and subsequent blindness. Early detection and prompt treatment can prevent blindness in up to 90% of patients. The common risk factors for diabetic retinopathy …
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Retinopathy of Prematurity in a cohort of neonates at Groote Schuur Hospital
Background: Screening for Retinopathy of Prematurity (ROP) is recommended to prevent possible blindness. Prior to 2016, resource limitations precluded routine ROP screening at Groote Schuur Hospital (GSH). Previous pilot studies at GSH did not detect ROP requiring treatment. However, improved …
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