Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"retinogeniculate"”.
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Mechanisms underlying retinogeniculate synapse formation in mouse visual thalamus
Retinogeniculate (RG) synapses connect retinal ganglion cells to the thalamic relay cells of the dorsal lateral geniculate nucleus (dLGN). They are critical for regulating the flow of visual information from retina to primary visual cortex (V1). RG synapses in dLGN are uniquely larger and stronger …
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The Role of Synaptically Evoked Plateau Potentials in Retinogeniculate Development
… refinement of sensory systems by using the mouse retinogeniculate system as a model. Spontaneous retinal waves lead to robust excitatory post-synaptic activity in developing relay cells in the dorsal lateral geniculate nucleus (dLGN) of the thalamus and are reportedly needed to help guide the …
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Influence of the target on development of the ferret retinogeniculate projection
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1991.
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The development of functional inputs to a neural circuit : synaptic strength before and after the activity-dependent maturation of the retinogeniculate system
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1999.
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Circuit Development in the Dorsal Lateral Geniculate Nucleus (dLGN) of the Mouse.
… the brain. Studies thus far have focused on the retinogeniculate pathway and the development of connections between retinal ganglion cells (RGCs) and relay cells has been well characterized. However, there are still a number of unanswered questions about circuit development in dLGN. Here we …
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Role of retinal inputs and astrocytes for the development of visual thalamus
… morphological properties and functionality at retinogeniculate synapses early in development, by eye-opening and before visual experience. These studies reveal that while experience-dependent visual activity from RGC axons is critical for many aspects of visual thalamus development, astrocytic …
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Influence of retinal states on the development and maintenance of retinofugal projections
… profile suggests activity may instruct early retinogeniculate development. nob mice, which also exhibit impaired OPL transmission, have aberrant retinal waves that align with loss of segregation. nobxGβ5-/- mice have similar levels of segregation as Gβ5-/- at P21, but activity only similar P14 …
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The role of EphrinA for the retinotopic map formation in mouse visual cortex
… brain systems including the retinotectal and retinogeniculate projection. Much less is known about mechanisms that are important for the formation of topographic maps in the cortex. This study has investigated the role of ephrin-A ligands for the formation of the retinotopic map in the primary …
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The Albino Mouse Visual System: How Perturbed Retinal Development Leads to Altered Binocular Projections
… specification in the albino mouse. Analysis of retinogeniculate targeting in the albino mouse revealed a population of contralateral VT RGCS that forms an abnormal patch of terminals in the dorsal lateral geniculate nucleus (dLGN) of the mouse, suggestive of misspecification of RGCs in this …
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Towards Mammalian Retinal Regeneration: Cell Signaling in Re-Differentiating Mouse Müller Glia and Transcriptional Regulation of the Axonal Guidance Receptor EPHA5
… (B2m), which has been implicated in retinogeniculate synaptic remodeling. Thus POU4F2 may repress B2m expression, but does not regulate EphA5, EphA6, or Klf16 expression. In conclusion, in vitro differentiation of ImM10 Müller glia results in conflicting activation of MAPK and STAT3 …
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DEVELOPMENTAL REMODELING OF RELAY CELLS IN THE DORSAL LATERAL GENICULATE NUCLEUS (dLGN) OF THE MOUSE AND THE ROLE OF RETINAL INNERVATION
The dorsal lateral geniculate nucleus (dLGN) has become an important model for studying many aspects of visual system development. To date, studies have focused on the development of retinal projections and the role of activity in shaping the pattern of synaptic connections made with …