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Showing 1 to 2 of 2 for “"retinal release"”.

  1. Molecular Evolution and Functional Characterization of the Visual Pigment Proteins of the Great Bowerbird (Chlamydera nuchalis) and Other Vertebrates

    … hydroxylamine sensitivity and the rate of retinal release. This chapter includes an investigation into the role of amino acid mutations typical of dim-light adapted vertebrates, D83N and A292S, in regulating functional properties of bovine and avian RH1s using site-directed mutagenesis. …

    toronto-retro Repository record for Molecular Evolution and Functional Characterization of the Visual Pigment Proteins of the Great Bowerbird (Chlamydera nuchalis) and Other Vertebrates (opens in a new tab)

  2. Development of Novel Chemical Biology Tools for Probing Structure-Function Relationships in G Protein-Coupled Receptors

    … Rho consists of a chromophore ligand, 11-cis-retinal, bound to the opsin via a Schiff base bond. The photoisomerization of 11-cis-retinal to all-trans-retinal activates the receptor to trigger the downstream signaling cascade in photoreceptor cells. The Schiff base bond in the active …

    rockefeller Repository record for Development of Novel Chemical Biology Tools for Probing Structure-Function Relationships in G Protein-Coupled Receptors (opens in a new tab)