Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"retinal ischemia"”.
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Experimental porcine models of retinal ischemia
Retinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. The aim of this …
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Retinal Ischemia in the In Vivo Rodent: Cellular and Vascular Characteristics
Retinal vessel occlusion is among the leading causes of vision loss. The functional and cellular effects of acute loss of blood flow have not been investigated fully, and current treatments only address secondary complications of ischemic damage. This work has developed new tools with which to …
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Retinale Ischämie bei der intraluminalen Fadenokklusionsmethode
… an established model to induce a focal cerebral ischemia. Considering the blood supply of the retina, the induction of a retinal ischemia with the intraluminal suture methode (ILSM) is possible. In this experiment we induced a transient retinal ischemia in Sprague-Dawley-rats by occluding the …
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The traditionally protective cystathionine gamma-lyase/hydrogen sulfide pathway contributes to pathological retinal neovascularization in oxygen-induced retinopathy
… to protect against oxidative stress, attenuate ischemia/reperfusion injury, and promote angiogenesis, functions which are typically beneficial in ischemic tissue. However, retinal ischemia can cause pathological vessel growth which disrupts the precise ocular architecture and leads to …
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Inflammatory mediators in diabetic retinopathy
… vessel strands, micro-occlusions, progressive ischemia, and finally the appearance of neovascularization and fibrosis. Hyperglycemia in the retina activates pro-inflammatory pathogenetic pathways i.e., the polyol, PKC, hexosamine, and RAS pathways, as well as AGE formation. Molecular changes …