Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"response induction"”.
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IMPACT OF DRP1 ACTIVATION, UNFOLDED PROTEIN RESPONSE INDUCTION AND FGF21 LEVELS IN DMD PROGRESSION
… UPR (UPRmt) and a muscle-specific induction of the stress mitokine FGF21. FGF21 detrimental effects have been reported concerning bone loss in mdx mice however it could also impact fibro-adipogenic progenitors differentiation considering that these cells express FGF receptor. We …
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The Pursuit of Unshocking Hsp90 Inhibitors: Development of Gedunin and Cruentaren A as Chemical Leads
… client protein degradation and cause the induction of the heat shock response that results in an upregulation of Hsp90 and other Hsp expression levels following incubation within cells. As a result, untoward toxicological effects are observed and the determination of appropriate dosing …
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Mechanics of Stimulus & Response Generalization in Signal Detection & Psychophysics: Adaptation of Static Theory to Dynamic Performance.
… of reinforcement along both stimulus and response dimensions. Historically the majority of research has addressed situations in which the difference among stimuli and resulting consequences of a perceptual decision are static. Consequently, little is known about the dynamics of stimulus …
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Lipid raft signaling in cofilin-actin rod formation induced by amyloid-β and TNFα
… not as a quantitative measure of the total rod response. Induction of cofilin-actin rods by amyloid beta and TNFα is mediated by the cellular prion protein, a component of lipid raft domains which can signal to activate NADPH oxidase. Lipid rafts are cholesterol/sphingolipid enriched detergent …
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Molecular regulation of the induction of cytochrome P-450E in the estuarine fish Fundulus heteroclitus
Induction of the aryl hydrocarbon hydroxylase (AHH) P450IA1 occurs in many organisms following exposure to polycyclic aromatic hydrocarbons (PAH). Regulation of induction of P450IA 1 (called P-450E) was examined in the estuarine teleost Fundulus heteroclitus. Antibodies were a primary tool in this …
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Molecular Basis of Upregulation of IL-17 in Estrogen Model of Inflammation
… a major role in inflammation by regulating the induction of various proinflammatory genes, which aid in the recruitment and activation of neutrophils. Although IL-17 is considered to be protective in infection, overproduction of IL-17 in conditions like autoimmune diseases has been shown to …