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Showing 1 to 10 of 10 for “"resistant hypertension"”.
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A novel approach for treating resistant hypertension using a controlled-pump accumulator relief device
Hypertension contributes to cardiovascular morbidity and mortality worldwide. While many hypertensive patients respond to drug therapy, a growing number of these cases are called resistant hypertension (RH), when patients cannot control their blood pressure to goal levels despite the use of …
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Pharmacogenetics of resistant hypertension: evaluating the role of genetic variation in ABCB1, ADBR1, CES1, CYP3A4, CYP3A5, NEDD4L, NOS3, NR3C2 and SCNN1B among South African hypertensive patient
… that over one billion individuals live with hypertension. The prevalence of resistant hypertension can be as high as 19% among African populations. Genetic variation in genes that affect the metabolism and transport of antihypertensive drugs has been reported to influence treatment outcome in …
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Corticosteroid hormone action in the cardiovascular system
… in disorders such as primary hyperaldosteronism, resistant hypertension and congestive heart failure (CHF) but the underlying molecular mechanisms of corticosteroid hormone action remain unclear. We have characterised corticosteroid hormone action and metabolism by 11β- …
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Rezistentiška arterine hipertenzija sergančių pacientų įvertinimas koregavus medikamentinį gydymą bei po simpatinės inkstų arterijų denervacijos /
Arterial hypertension (AH) is a major risk factor for cardiovascular disease, stroke, disability, and overall mortality., however, some patients are still failing to meet their target blood pressure values. The aim of this research was the need for detailed examination and selection of patients …
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Evaluation of patients with resistant arterial hypertension before and after pharmacological treatment correction or a renal artery sympathetic denervation procedure /
Arterial hypertension (AH) is a major risk factor for cardiovascular disease, stroke, disability, and overall mortality., however, some patients are still failing to meet their target blood pressure values. The aim of this research was the need for detailed examination and selection of patients …
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Cardiovascular magnetic resonance characterisation of the phenotype of resistant uncontrolled hypertension
Background: Resistant hypertension (RH) is defined as blood pressure (BP) that remains elevated (>140/90mmHg) despite being treated with an antihypertensive regimen of 3 or more medications from different classes, including a long-acting calcium channel blocker, an angiotensin converting enzyme …
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Identifikation von potentiell prädiktiven biochemischen Faktoren für den Erfolg der renalen Denervation bei therapierefraktärer Hypertonie und ihre Veränderung nach Intervention
Hintergrund: Die renale Denervation gilt als ein sicheres Verfahren zur Behandlung von therapieresistenter Hypertonie, es ist jedoch noch nicht hinreichend erklärt, welche Faktoren zu einer unzureichenden Blutdrucksenkung nach der renalen Denervation führen und welchen Einfluss das Verfahren auf …
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Role of two genes, CACNA1D and CADM1, with common or rare mutations in aldosterone producing adenomas of the adrenal.
… aldosteronism (PA) accounts for 5-10% of all hypertension. One of the major causes of PA is sporadic formation of aldosterone-producing adenomas (APAs). These benign tumours develop in the cortical region of adrenal glands and autonomously secrete excessive amounts of aldosterone. This hormone …
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Renal failure and the neural control of the kidney
Renal failure (RF) is associated with an over activation of the sympathetic nervous system. The aim of this thesis was to investigate the hypothesis that as the kidney progresses into RF there is an inappropriate and sustained activation of renal afferent nerves which results in a dysregulation of …