Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"residue networks"”.
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Structural and Computational Studies of RNA Polymerase
… we lack information about the hidden functional residue networks that underlie the activities of this complex multi-subunit molecular machine. By combining structural and computational methods we: (1) Used X-ray crystallography to investigate promoter -35 element recognition by domain 4 of the …
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The molecular basis for evasion of antibody-mediated neutralization in flaviviruses
… is long-range communication connecting distant residues linked to the viral epitope. Mutations at sites distant but coupled to the epitope would lead to an alteration of affinity to antibody; e.g., resistance to antibody-mediated neutralization. In support of our hypothesis, we demonstrated by …