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RNA replication by poliovirus RNA-dependent RNA polymerase: effects of residue 5 on elongation complex stability and processivity

Hobdey, Sarah Elizabeth, author, Peersen, Olve B., advisor, Stargell, Laurie, committee member, Chen, Chaoping, committee member, Wilusz, Carol, committee memberColorado State University. Libraries2011

… Specifically, my work shows that the PV RdRP residue 5 is involved in forming and maintaining the stable, elongation-competent complex. Also, the complex stability can be modulated by downstream RNA interactions or by the number of nucleotides that are incorporated to form the stable complex. …

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