Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"residual dipolar couplings"”.
-
Dynafold: A Dynamic Programming Approach to Protein Structure Calculation From Residual Dipolar Couplings
… crystallography. A new type of NMR restraint, residual dipolar couplings (RDCs), has shown promise as a source of data for large classes of proteins including transmembrane proteins.</p> <p>To date, most methods of utilizing residual dipolar couplings as structural re- straints have centered …
-
Moderne Festkörper-NMR an Funktionspolymeren
… techniques. This interactions, the so-called residual dipolar coupling, are a measure of the polymer dynamics. In the project on natural rubber, it was possible for the first time to determine the heteronuclear dipolar couplings between 1H and 13C nuclei. This was not possible so far, on the …
-
NMR of elastomers and biological tissues
… AIMS (Accordion Magic Sandwich), which scan the dipolar magic echo shape with the Hahn echo, was developed. Using this method the residual second and fourth van Vleek moments, which are more sensitive to cross-link density, were measured, model free, without the interference originated from …
-
NMR application and development : study of the ribosomal RNA-L11 complex
… number of orientational restraints derived from residual dipolar couplings in addition to conventional NOE-based restraints. The solution structure of L11 demonstrates that in contrast to many other multi-domain RNA- binding proteins, the relative orientation of the two domains is well defined as …
-
Determination of Biomolecular Interdomain Motions using Nuclear Magnetic Resonance
… of interdomain orientations, we measured residual dipolar couplings (RDCs) from the two domains with multiple alignments. The N-terminal domain was directly aligned by a lanthanide ion and not influenced by interdomain motions, so it acted as a reference frame to achieve motional …
-
Structure determination of proteins and peptides in solution: simulation, chirality and NMR studies
… from a protein. In this context, the effect of Residual Dipolar Couplings (RDCs) in the structure refinement was shown, revealing a strong improvement of structure resolution. A wide extent of this thesis is devoted to the study of avian prion protein. Prion protein is the main responsible of a …
-
Building Better Backbones: Visualizations, Analyses, and Tools for Higher Quality Macromolecular Structure Models
… for calculating core protein models from NMR residual dipolar coupling (RDC) data. Third, I describe how 3D visualization of RDCs in their structural context improves understanding of RDCs and validates NMR models in a novel way. Fourth, I describe how local quality analysis can diagnose …
-
Advanced NMR analysis of polymers and biomolecules
… sequence was used for measuring site-selective residual dipolar couplings in cross-linked natural rubber. A theoretical description of this method based on the evolution of the density operator was developed for an arbitrary value of the pulse flip angle. The method allows fast NMR experiments, …