Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"rescue effect"”.
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Biogeographical patterns of southern African marine invertebrates
… productivity, competition, predation, stability, effective evolutionary time, niche breadth, range size and area of occupancy. Evidence exists that both supports and negates most of these mechanisms. In addition to the richness gradient, a latitudinal gradient in geographical range size exists, …
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Mechanisms of Impaired Efferocytosis of Synovial Macrophages in Knee Osteoarthritis
… decreased and that targeting these pathways can rescue the defect. To study the specific altered mechanisms, this study used macrophages differentiated in vitro from primary blood monocytes, which were treated with synovial fluid from patients with high levels of inflammation due to knee OA. By …
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rd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration
… no photoreceptors left. In order to study the effect of factors which delay or halt the photoreceptor degeneration, a long term retina organ culture has been used. The culture medium of this culture paradigm was devoid of fetal calf serum (FCS) as FCS by itself contains an unknown number of …
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Exploring the influence of adipokines on neuronal function in Alzheimer’s disease
… was focused on the potential neuroprotective effect of adipokines on the neurons during hydrogen peroxide (H2O2) induced oxidative stress and cell death. In this study, human neuroblastoma SHSY5Y cells were differentiated using retinoic acid to demonstrate neuronal-like characteristics which …
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Understanding the Differential Effects of Dexamethasone on the Metabolism of Healthy and Diseased Articular Cartilage
… reports on Dex efficacy often disagree on the effects of Dex on cartilage tissue homeostasis. The first part of this thesis uses proteomic analyses of a bovine ex vivo cartilage explant monoculture model of PTOA progression to identify inflammation-induced catabolic processes associated with …
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Mitochondrial Instability, Lack of Erk1/2 Activation and High Expression of P75NTR in Engrailed-Deficient Mesencephalic Dopaminergic Neurons
… addition of an inhibiting antibody for P75. The rescue effect of these survival factors is diminished by concurrent treatment of the primary cell cultures with an inhibitor of the extracellular signal regulated kinase1/2 (Erk1/2) pathway. Additionally, there is an inverse correlation between …
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Probiotic Modulation of Mucosal Immune Responses in an In Vitro Co-Culture Model
… were firstly to investigate the immunomodulatory effects of a panel of heat-killed (HK) probiotic bacteria and their secreted proteins (SP) of Bifidobacterium breve (BB), Lactobacillus rhamnosus GG (LR), L. salivarius (LS), L. plantarum (LP), L. ferrmentum (LF), and L. casei strain Shirota (LcS) …
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Engrailed genes are cell autonomously required for the survival of the mesencephalic dopaminergic neurons
… and verify whether the absence of any rescue effect of the mDA neurons from the wild-type neuroepithelium was not a result of a pre-commitment to cell death, at the time of dissociation, we silenced En-1 by RNAi in En-2-/- ventral midbrain cultures. We observed, thereby, that in En-1 …
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Connectivity, metapopulation dynamics, and genetic structure of tiger salamanders in a heterogeneous landscape
… theory is neutral with respect to the effects of habitat heterogeneity on population processes. Landscape ecology approaches have begun to account for effects of habitat quality and matrix structure on occupancy and gene flow, but few empirical studies have integrated the area-isolation …
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Artificial Night Lighting and Anthropogenic Noise Alter Animal Activity, Body Condition, Species Richness, and Community Structure
… remote or protected areas are not immune to the effects of increased sensory disturbances with 63 percent of protected areas within the United States found to have been exposed to a doubling of background noise levels due to anthropogenic activity and skyglow, the scattering of artificial light …
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Functional genomics of plant compensatory responses
… of four complementation lines showed a partial rescue effect of G6PDH1, showing patterns more similar to the overcompensating Columbia line than either Landsberg erecta or the knockout line. Furthermore, results of our promoter-reporter fusion studies (G6PDH1 promoter: β-glucuronidase (GUS)) and …