Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"reproductive toxicology"”.
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Circulating sex hormone levels in rats: a systematic analysis of the literature and perinatal BPA study
In the study of reproductive toxicology, animal models play an important role in elucidating the mechanisms by which a toxicant exerts its deleterious effects, as well as serving as a translational system for comparison to human biology. The anatomy, physiology, and molecular mechanisms of the …
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Mechanisms by which di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate disrupt ovarian folliculogenesis and steroidogenesis
… are known endocrine disrupting chemicals and reproductive toxicants in the female. The ovary is a primary regulator of the female reproductive and endocrine systems. Thus, proper regulation of ovarian function is required for reproductive health and steroid hormone controlled non-reproductive …
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The effects of propylparaben on preimplantation embryo development
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Effects of Quaternary Ammonium Disinfectants on Mouse Reproductive Function
… these compounds have been used for decades, reproductive toxicity has not been thoroughly evaluated. Extensive use of QACs results in ubiquitous human exposure to potentially toxic compounds. Reproductive toxicity of two common QACs, alkyl dimethyl benzyl ammonium chloride (ADBAC) and didecyl …
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Prenatal exposure to phthalates accelerates reproductive aging in multiple generations of female mice
… have also shown that phthalates may accelerate reproductive aging. Reproductive aging in females is characterized by biomarkers including a drastic decrease in the ovarian follicle pool, dysregulation of hormones involved in the hypothalamic-pituitary-gonadal (HPG) axis including sex steroids, …
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Machine learning in predictive toxicology: investigating developmental and reproductive toxicity with transfer learning
… products or drugs. In the field of predictive toxicology, with animal testing being phased out in some sectors, there is an urgent need for alternative methods for determining toxicity. An *in silico* method such as machine learning is one such popular choice given that the results can be …
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Toxicity and detoxification of imidacloprid in mouse ovarian follicles
… Although some evidence exists that IMI is a reproductive toxicant, there are many unanswered questions regarding the effects of IMI on the ovaries. Thus, the studies described in my dissertation were designed to test the hypothesis that IMI causes ovarian follicle toxicity via acetylcholine …
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The immediate and long-term consequences of temporary exposure during adulthood to di(2-ethylhexyl) phthalate and diisononyl phthalate on female reproduction
… that target the ovary can lead to disruptions in reproductive and overall health. The phthalate chemical family has several prominent members with endocrine disrupting capabilities. One of the most common phthalates is di(2-ethylhexyl) phthalate (DEHP), with up to 100 million pounds produced …