Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"reproductive medicine"”.
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Outcome of assisted reproductive technology in women with poor ovarian response undergoing infertility treatment in the reproductive medicine unit of Groote Schuur hospital: a five-year review
Background: Poor response of the ovaries to gonadotropin stimulation is associated with poor outcome following in vitro fertilization. The historical lack of a standard definition for poor ovarian response has resulted in a wide variation in prevalence and outcome measures. More recently, the …
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Barren promise : the hope and heartache in treating infertility
Preimplantation Genetic Diagnosis (PGD) is a reproductive medicine technology that allows the genetic characteristics of embryos to be examined. Created through in vitro fertilization, embryos are grown in a Petri dish for three days, at which point they have eight cells. One cell is then removed …
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Against Eternity: A Critical Reading of Transhumanism
… a eugenic link between transhumanism and reproductive medicine. I then reveal how contemporary transhumanism functions through a paradigm of potential wherein value is determined by the speculations of venture capitalism. Analyzing the future-oriented rhetoric in both “afterlife” …
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Strategies to improve artificial insemination by donor
… randomised clinical trail was undertaken in the Reproductive Medicine Unit at Groote Schuur Hospital to compare intrauterine insemination with intracervical insemination in a therapeutic donor insemination program with cryopreserved semen. The method of insemination was alternated in successive …
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Understanding Attitudes toward In-Vitro Fertilization and Support for Less Restrictive In-Vitro Fertilization Policies: The Influence of Family, Information Processing, Media, and Science
The emergence of in-vitro fertilization (IVF), a reproductive technology, has allowed infertile women and couples the opportunity to conceive children and form much desired families. Increased media exposure and political attention have aroused public concern and controversy, especially within the …
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Post-vasectomy semen analysis: Follow-up of patients at three Cape Town Metropole facilities.
… post-vasectomy semen analysis (PVSA) from the Reproductive Medicine Unit at Groote Schuur Hospital. Results: Our study population included 270 patients who had vasectomies from September 2016 to July 2021. Only 122 (45.2%) PVSA results from those patients that adhered to the follow-up protocol …
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Current Practices and Perspectives of Genetic Counselors and Reproductive Endocrinologists Regarding Transfer of Mosaic Embryos
… patients. The current landscape of this area of reproductive medicine must be described before a consensus can be determined and areas for improvement can be identified. This cross-sectional descriptive study aimed to define the current practices regarding TME as reported by prenatal and/or …
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Beyond the petri dish: potentiality in assisted conception in South Africa
… as they materialise in concrete instances of reproductive medicine that is entangled within a context of capitalist biomedicine. Here, I argue that while biomedical knowledge systems frame certain objects, times, and futures as having potential, it simultaneously negates and neglects other …
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MULTISCALE TECHNOLOGIES FOR ENGINEERING AND CRYOPRESERVING OVARIAN TISSUES AND HUMAN IPSCs
An estimated 9.8 million reproductive-age people with ovaries in the United States are impactedby fertility issues, oftentimes caused by the dysregulation of the tightly controlled process of ovarian follicle development. Impaired fertility can arise from disorders like polycystic ovarian syndrome …
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Justifying Bioethical Case Decisions: Reflective Equilibrium and Mid-Level Moral Principles
… medical practice in the field of assisted reproductive medicine. In descriptions of over forty cases, I show the difficulty this committee faced in solving routine cases and even more when attempting to solve the novel cases that arise with some frequency in this unique field. This research …
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Reproductive function in young Swedish men - Time trend, prenatal and adult exposure to smoking and phthalates
A decrease in male reproductive function, including sperm counts, during the second half of the 20th century, has been postulated. During this period, testicular cancer has increased several-fold. Environmental and lifestyle-related factors have been proposed as explanations for a possible negative …
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Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone
Declining birthrates and infertility are now a common problem in the Western World. Due to the tendency to postpone childbearing an increasing age of women who consider motherhood is generally seen. A factor closely related to female fertility is the ovarian reserve, a term used to designate both …
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Using an Integrated Decision-making Framework to Identify Factors Associated with Receipt of a Fertility Consultation by Canadian Female Cancer Patients
… providers in the areas of both oncology and reproductive medicine. This study provides insight into the process that Canadian female cancer patients use to make their fertility preservation decisions in a stressful time-pressured situation. It also explores the validity of the newly developed …
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Strategies to improve in vitro maturation of human and mouse oocytes
Our knowledge of reproductive medicine has expanded rapidly since the birth of Louise Brown, the first baby to be conceived by in vitro fertilization (IVF) in 1978. In vitro maturation (IVM) of oocytes - a culture technique to support maturation of immature oocytes in vitro - could offer an …
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Protein Phosphatase 4 in human spermatozoa: investigations into location, regulatory subunits and role in motility
… by the WHO since 2004. The American Society of Reproductive Medicine cites 50% of infertility diagnosis as being of male factor origins. Surprisingly, there is very little that can be done to tackle the problem of male infertility. The key to progression in this field will be the translation of …
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Out of pocket payment for assisted reproductive techniques: How to households recover?
… was carried out at the Infertility Clinic of the Reproductive Medicine Unit, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town. All 135 participants from the original study were invited to participate with no exclusion criteria. A six part questionnaire, developed for …
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A Study of Guideline for Genetic Counselling in Preimplantation Genetic Diagnosis (PGD)
… The application of PGD to genetic practices and reproductive medicine, genetic counseling is becoming the key component, because of the need to develop the custom made design of PGD for each couple. In this study, the survey for the contents of genetic counseling in PGD was carried out by direct …
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Pain and fertility outcomes post endometriosis surgery at Groote Schuur hospital
… disorder and affects millions of women in their reproductive age. The true incidence is not well known but it is around 6% or more. The clinical presentation of endometriosis varies. Most women will present with secondary dysmenorrhea, dyspareunia, pelvic pain, and infertility. Laparoscopy is the …
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New predictive and diagnostic biomarkers for preeclampsia
Abstract Preeclampsia is a serious pregnancy complication that affects 3-8% of all pregnancies leading to maternal- and fetal morbidity and mortality. The etiology is still not known in detail. Previous findings have shown an up regulation of the genes coding for fetal hemoglobin (HbF) in …
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Ultrasound Studies of Caesarean Hysterotomy Scars
The aim of the work presented in this thesis was to investigate how transvaginal ultrasound examination of non-pregnant women could be used to visualize and assess caesarean hysterotomy scars, and to evaluate the risk of uterine rupture in subsequent pregnancies. The diagnostic value of …
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