Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"replication bypass"”.
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Biological Consequences Of Complex Dna Lesions Induced By Bis-Electrophiles
… and genomic integrity by interfering with DNA replication and transcription. Unless repaired, they can be misread by DNA polymerases, leading to heritable mutations and cancer. Amongst known human carcinogens is 1,3–butadiene (BD), an important industrial chemical and environmental pollutant. …
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DNA-Protein Cross-links: Formation, Repair, and Inhibition of DNA replication
… disrupt regular DNA cellular machinery, such as replication, transcription, and repair, leading to mutagenesis and carcinogenesis. DPCs can also form endogenously when naturally occurring epigenetic marks (5-formyl cytosine, 5fC) in DNA react with lysine and arginine residues of histones H2A, H3, …