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Showing 1 to 20 of 271 for “"reperfusion"”.

  1. Therapeutic strategies for ischemia reperfusion injury

    Eskla, Kattri-Liis2019

    tartu

  2. INTRA-MITOCHONDRIAL INJURY DURING ISCHEMIA-REPERFUSION

    Aluri, Hema2018

    Cardiac injury is increased following ischemia-reperfusion. Mitochondria are the “effector organelles” that are damaged during ischemia (ISC) when there is no blood flow. Resumption of metabolism by damaged mitochondria during reperfusion (REP) results in increased cell injury. Current therapeutic …

    vcu Repository record

  3. Mitochondrial Metabolism in Ischaemia Reperfusion Injury

    Huang, Margaret MaUniversity of Cambridge2024

    Ischaemia reperfusion (IR) injury is caused by the re-introduction of oxygenated blood flow to tissues after a period of ischaemia. It is an inevitable consequence of organ transplantation, where its severity contributes to reduced levels of graft function and survival. There are no clinically …

    cambridge Repository record

  4. Treatment of Ischemia Reperfusion Injury with RNA Interference

    Zwiep, Terry MThe University of Western Ontario2015

    Ischemia reperfusion injury (IRI) occurs during transplantation and causes apoptosis and inflammation. The purpose of this research was to determine the effect of caspase-3, complement 3, and RelB gene silencing in the reduction of IRI using an in vitro model. LLC-PK1 cells were used along with …

    uwo Repository record

  5. Ribonomic Control During Global Brain Ischemia And Reperfusion

    Wang, Haihui2014

    … CONTROL DURING GLOBAL BRAIN ISCHEMIA AND REPERFUSION</p> <p>by HAIHUI WANG</p> <p>August 2014</p> <p>Advisor: Donald J. DeGracia, Ph.D.</p> <p>Major: Physiology</p> <p>Degree: Doctor of Philosophy</p> <p>The study presented here used "omic" technology to look at the mechanism behind the …

    wayne-thes Repository record

  6. Novel Strategies in Cardioprotection against Ischemia/Reperfusion Injury

    Salloum, Fadi N.2014

    … where it plays an important role in ischemia-reperfusion (I/R) injury. Considerable progress has been made towards identifying physiological and pharmacological agents that play a key role in myocardial preconditioning against I/R injury and also elucidating the molecular changes leading to …

    vcu Repository record

  7. Superoxide and nitric oxide in ischemia-reperfusion injury.

    Skinner, Kelly Ann

    uab Repository record

  8. Novel Protective Agents against Cerebral Ischemia/Reperfusion Injury.

    Xu, Xingshun2007

    … HNG reduced infarct volume after ischemia/reperfusion injury with pre-treatment or post-treatment (i.c.v. and i.p.) in a middle cerebral artery occlusion model in mice and decreased neurological deficits induced by ischemia. The protection of HNG was mediated by inhibiting ERK activation …

    etsu Repository record

  9. Flavonoid protection of cardiac cells against ischemia-reperfusion injury

    Akhlaghi Najafabadi , MasoumehUniversity of Saskatchewan2008

    Myocardial ischemia-reperfusion injury occurs following the majority of cardiac events including myocardial stenosis and heart surgeries. As reactive oxygen species are one of the major contributors to ischemia-reperfusion injury, strategies to prevent their effects may be directed towards …

    sask Repository record

  10. Analyse der Thrombozyten-Endothelzell-Interaktion bei hepatischer Ischämie-Reperfusion

    Khandoga, AndrejLudwig-Maximilians-Universität

    96 Der hepatische Ischämie-Reperfusionsschaden stellt ein relevantes klinisches Problem nach Lebertransplantation und Leberteilresektion sowie nach hämorrhagischem Schock dar. Es gibt zunehmend Hinweise darauf, daß Thrombozyten an der Ausbildung des hepatischen Ischämie-Reperfusionsschadens …

    lmu-germany Repository record

  11. Improvement of liver transplantation by reducing preservation-reperfusion injury

    van As, Arjan BastiaanDepartment of Surgery1999

    … artery and venous blood via the portal vein. The reperfusion injury which occurs after ischemia, has been studied to only a limited extent in the liver. In particular, the relative contribution of the portal venous blood and the hepatic arterial blood to the reperfusion injury has not been …

    cape-town Repository record

  12. Indole based antioxidants for the treatment of ischemia reperfusion injury

    Chapp, Andrew

    mtu Repository record

  13. Early Mediators of Cutaneous Ischemia Reperfusion Injury: A Mouse Model

    Pruitt, Christopher Rogers2014

    … to be the repetitive incidence of ischemia reperfusion injury.A mouse model of cyclic ischemia reperfusion was employed to examine the initiation events in the pathology of chronic wounds. Mice were subjected to eight hours of magnetic skin compression via four cycles of two-hours ischemia …

    vcu Repository record

  14. Cardiovascular Risk, Remote Ischemic Postconditioning, and Endothelial Ischemia-Reperfusion Injury

    Hemenway, Brian A.2017

    … stimulus that is thought to reduce reperfusion injury associated with heart disease. However, certain animal models of cardiometabolic risk factors such as dyslipidemia, diabetes, and hypertension suggest the beneficial effects of rIpost to lessen reperfusion injury may be …

    sdstate Repository record

  15. The central role of the neutrophil in ischaemic/reperfusion injury

    Buck, Nicola S.Aston University1998

    … models of the sequential stages of ischaemia/reperfusion injury were examined. Methods were initially developed to examine the adhesion of neutrophils to monolayers of a cultured endothelial cell line (ECV304) after periods of hypoxia and reoxygenation. Neutrophil migration in response to …

    aston Repository record

  16. Mitochondrial Dynamics: Exploring A Novel Target Against Myocardial Ischemia-Reperfusion Injury

    Dong, Yi2020

    … mediator of cell fate in the setting of ischemia-reperfusion (IR) injury, and, ii) inhibition of DRP1 and mitochondrial fission provides cardioprotection against IR injury. However, the precise role of DRP1 translocation to mitochondria in the pathogenesis of myocardial ischemia-reperfusion injury …

    wayne-thes Repository record

  17. Investigation Of Posttranscriptional Regulation After Global Brain Ischemia And Reperfusion Injury

    Szymanski, Jeffrey J.2012

    … revived after cardiac arrest is ischemia and reperfusion (I/R) injury in the brain. Survival after brain I/R injury depends on the expression of new stress response proteins such as heat shock protein 70 (HSP70). Little is known about why recovering neurons are able to express new stress …

    wayne-thes Repository record

  18. Mechanisms of persistent translation arrest following global brain ischemia and reperfusion

    Jamison, Jill Theresa2011

    … ARREST FOLLOWING GLOBAL BRAIN ISCHEMIA and REPERFUSION</p> <p>by</p> <p>JILL T. JAMISON</p> <p>December 2011</p> <p>Advisor: Donald J. DeGracia, Ph.D.</p> <p>Major: Physiology</p> <p>Degree: Doctor of Philosophy</p> <p>The information presented here studies the mechanisms that underlie …

    wayne-thes Repository record

  19. Proteomic Discovery of Functionally Important Pathways in Myocardial Ischemia-Reperfusion Injury

    Ahmed, Kamran2019

    The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.

    utswmed Repository record

  20. α-Lipoic Acid Attenuates Ischemia Reperfusion Injury of the Rat Liver

    Müller, ChristianLudwig-Maximilians-Universität

    107 Ischemia reperfusion injury (IRI) represents a major clinical problem in liver transplantation and resection. Main pathophysiological events during this injury comprise depletion of ATP, Kupffer cell activation with subsequent formation of reactive oxygen species and inflammatory response. …

    lmu-germany Repository record

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