Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"renal development"”.
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Effect of pre-natal overnutrition on renal development in the rat
Thesis (M.S.)--Michigan State University. Dept. of Food Science and Human Nutrition, 1976
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The PI3-Kinase/TSC Pathway: A Role in Neural and Renal Development and Pathology
… PTEN and TSC1 in both post-mitotic neurons and renal tubule cells, and evaluated the relationship of these two tumor suppressor genes in two distinct contexts. Previously, a conditional Pten knockout mouse line was generated with Pten loss in limited post-mitotic neurons in the cortex and …
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Advanced in vivo imaging of the interactions between vascular and renal development in the zebrafish pronephric kidney
BACKGROUND Heart disease and renal dysfunction are often mutually reinforcing conditions, although the factors underlying this relationship are not fully understood. Cardiac remodelling resulting from disease is partly caused by the reactivation of developmental programmes. By unravelling the …
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The Study of Nitric Oxide Synthase Expression, Function, and Regulation in the Renal Vasculature During Postnatal Renal Development
… newborn kidney is vulnerable to vasomotor acute renal failure (ARF) from adverse perinatal events or complications of prematurity. Nitric oxide (NO) vasodilation is vitally protective in this type of ARF, but its relationship with other vasoactive factors, such as angiotensin II (AII) has not …
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Impact of Differentiation Status of Kidney Progenitors In Wilms Tumor Development
… and is thought to arise from undifferentiated renal mesenchyme. However, the differentiation status of cells in the mesenchyme that can give rise to Wilms tumors is unknown. Gene expression analysis of a large panel of Wilms tumor patients has identified different subsets of Wilms tumors that …
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Identifying the Origin of Zebrafish (Danio rerio) Renal Progenitor Cells
… from the human kidney by the presence of adult renal progenitor cells (RPCs) that are capable of neonephrogenesis. These cells can be labeled with eGFP in the Tg(lhx1a:egfp) transgenic line. Using this transgenic line, zebrafish kidney regeneration was shown to utilize tubule repair mechanisms …
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Preeclampsia: The Roles of Acute Inflammation and Intrauterine Stress
… PE is characterized by hypertension and renal damage reflected by proteinuria and has significant morbidity to both mother and fetus. Maternal symptoms range from headaches, nausea, edema, to visual changes, but once maternal symptoms present, damage to the fetus has begun. Mothers who …
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Indagini strutturali e quantitative durante lo sviluppo del rene mediante l’utilizzo di elaborazione immagini
… growing. A very relevant aspect is the development of the kidney. Nephron number at birth has a relevant clinical importance with implications for long-term renal health. In recent years, the podocyte depletion hypothesis has emerged as an important concept in kidney pathology. Moreover, …
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Exploring the impact of maternal obesity on offspring renal morphology and later life health
… exposed to maternal obesity. Alterations in renal morphology in early life have been linked to hypertension and renal disease in adulthood in both epidemiological and animal studies. Therefore, a second aim of this thesis was to assess blood pressure, renal function and markers of renal …