Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"renal cell cancer"”.
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Radioimmunotargeting of Renal Cell Cancer using Monoclonal Antibody cG250.
Contains fulltext : 58758.pdf (Publisher’s version ) (Open Access)
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Retinoide in der Therapie des metastasierten Nierenzellkarzinoms : Untersuchungen am Modell multizellulärer Tumorsphäroide
The special problem of metastatic renal cell cancer is the extensive resistance against common oncological treatment strategies like radiation and chemotherapy. Through means of cytokine immunotherapy, by which the interactions between the organism and tumor cells are to be modified by the …
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Mismatch Repair Deficient Cancer Diagnostic Aspects in Colorectal Cancer and the Role of Urological Cancer in Lynch Syndrome
… PMS2). The identification of MMR defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment-predictive purposes. The aims of this thesis were to validate the application of the MMR index for the prediction of MMR deficiency in colon cancer (study …
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Chronic oxidative stress and susceptibility to renal carcinogenesis
… shared by multiple risk factors of kidney cancer. But there is no experimental evidence to show direct role of oxidative stress in kidney cancer. In this study, our main objective was to evaluate effect of H2O2-induced chronic oxidative stress on neoplastic transformation of normal human …
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Developing computational methods to enhance understanding in glioma progression
… information and opportunities towards studying cancer evolution and heterogeneity. This has helped to determine the origin of some cancers, identify evolutionary patterns and decide how to best treat and study some cancer types. This thesis first presents a longitudinal study of patient-matched …
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Investigating pseudohypoxia in renal cells deficient in fumarate hydratase.
… a primary role of altered metabolism in driving cancer. One of these enzymes, fumarate hydratase (FH), is found mutated in hereditary and leiomyomatosis and renal cell cancer syndrome, whereby affected cells are characterized by high subcellular accumulation of the metabolite fumarate. Fumarate …
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The generation of a human cell line to elucidate the role of Fumarate Hydratase loss in cancer
The reprogramming of cellular metabolism is an established hallmark of cancer, which enables cancer cells to survive, proliferate, and metastasize even under harsh environmental conditions. These cancer-associated metabolic changes can affect several pathways one of which is mitochondrial …
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Potential of metabolic MRI to address unmet clinical needs in localised renal cancer.
… of early-stage (localised and locallyadvanced) renal cancer. Renal cancer is the deadliest urological malignancy with a widening gap between incidence and mortality, which highlights the need to review the current guidelines. In particular, early-stage renal cancer is to be looked into as it is …
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Die komplizierte Nierenzyste
… Bei der Beurteilung von zystisch konfigurierten renalen Raumforderungen stellt die Differenzierung zwischen einer benignen Läsionen und einem soliden Nierenzellkarzinomen (RCC) immer noch ein erhebliches klinisches Problem dar. Trotz des Gebrauchs hoch entwickelter Untersuchungsgeräte wie CT und …